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Table 2 Effects of AbMIP and placebo on endothelial function, blood pressure and triglyceride

From: Effects of an L-arginine-based multi ingredient product on endothelial function in subjects with mild to moderate hypertension and hyperhomocysteinemia - a randomized, double-blind, placebo-controlled, cross-over trial

 

Placebo

AbMIP

Product effect

Pre supplementation

Post supplementation

∆ post-pre supplementation

Pre supplementation

Post supplementation

∆ post-pre supplementation

p-value

cohens d

lnRHI [index]

0.603 ± 0.274 (0.49–0.716)

0.552 ± 0.274 (0.439–0.665)

−0.052 ± 0.271 (−0.163–0.06)

0.481 ± 0.373 (0.327–0.635)

0.551 ± 0.339 (0.411–0.691)

0.070 ± 0.327 (−0.065–0.205)

0.047

0.642

systole [mmHg]

136.8 ± 7.9 (133.5–140.0)

133.2 ± 6.9 (130.4–136.1)

−3.5 ± 6.1 (−6.0–(−1.0)) a

137.4 ± 7.7 (134.2–140.6)

132.8 ± 9.1 (129.1–136.6)

−4.6 ± 6.6 (−7.3–(−1.8)) a

0.586

0.221

diastole [mmHg]

84.8 ± 4.2 (83.1–86.6)

83.5 ± 4.4 (81.7–85.3)

−1.4 ± 4.3 (−3.1–0.4)

83.2 ± 4.5 (81.4–85.1)

82.2 ± 5.9 (79.8–84.6)

−1.0 ± 3.3 (−2.4–0.3)

0.763

0.119

TG [mg/dl]

116.2 ± 53.0 (94.4–138.1)

116.3 ± 43.0 (98.5–134.0)

0.0 ± 38.3 (−15.8–15.8)

117.0 ± 46.5 (97.8–136.2)

103.0 ± 40.4 (86.3–119.6)

−14.0 ± 27.9 (−25.5–(−2.5)) a

0.108

0.533

 

Pre fat meal

post fat meal

∆ post-pre fat meal

Pre fat meal

post fat meal

post-pre fat meal

  

lnRHI [index]

0.552 ± 0.274 (0.439–0.665)

0.754 ± 0.261 (0.646–0.862)

0.202 ± 0.234 (0.106–0.299)

0.551 ± 0.339 (0.411–0.691)

0.873 ± 0.171 (0.802–0.943)

0.322 ± 0.384 (0.164–0.48)

0.201

0.659

  1. Effects of AbMIP and placebo on endothelial function, blood pressure and triglycerides before and after intervention and on postprandial endothelial function before and after high fat meal. Results are presented as mean ± standard deviation (95% CI). a is indicating significant post to pre supplementation changes within group and significant post to pre fat meal changes within group