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Table 1 The effects of A. rugosa extracts, acacetin and tilianin on APTT, PT, TT, and FIB in vitro (‾x ± s)

From: Chemical constituents and coagulation activity of Agastache rugosa

Groups

APTT (S)

PT (S)

TT (S)

FIB (g/L)

Blank

19.5000 ± 0.216

11.5750 ± 0.275

14.2750 ± 0.13

3.7250 ± 0.132

Breviscapine

22.5000 ± 0.216***

14.0000 ± 0.163***

20.7750 ± 0.15***

6.1633 ± 0.035***

Vitamin K1

16.5500 ± 0.129***###

10.9333 ± 0.115***###

13.5000 ± 0.26***###

4.6000 ± 0.145***###

Ar.TE

19.3750 ± 0.320###&&&

10.5000 ± 0.258***###&

14.5250 ± 0.19##&&&

6.7150 ± 0.153***###&&&

Ar.Pe

16.0500 ± 0.238***###&&

10.2500 ± 0.191***###&&&

18.6475 ± 0.20***###&&&

3.8350 ± 0.066###&&&

Ar.Ea

16.625 ± 0.222***###

11.0500 ± 0.238**###

17.2450 ± 0.19***###&&&

3.7175 ± 0.111###&&&

Ar.Bu

16.0967 ± 0.295***###&

10.8750 ± 0.275***###

15.2750 ± 0.25***&&&

3.9100 ± 0.071**###&&&

Acacetin

20.7225 ± 0.121***###&&&

12.5500 ± 0.311***###&&&

20.2750 ± 0.26***##&&&

2.8125 ± 0.142***###&&&

Tilianin

20.7500 ± 0.191***###&&&

12.2000 ± 0.082***###&&&

16.7475 ± 0.19***###&&&

3.1425 ± 0.111***###&&&

  1. Note: results were expressed as mean ± SD, n = 4. Compared with blank: *** P < 0.001; 0.001 < ** P < 0.01; Compared with breviscapine: ### P < 0.001; 0.001 < ## P < 0.01. Compared with Vitamin K1: &&&P < 0.001, 0.001 < &&P < 0.01, &P < 0.05