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Table 5 Effect of aqueous extract of C. occidentalis on blood lipid parameters

From: Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

Experimental groups

Lipid parameters (mg/dL)

TC

TG

VLDL-c

HDL-c

LDL-c

LDL/HDL

CT/HDL

HC rats + dH2O

156.09 ± 0.92

141.01 ± 0.63

28.21 ± 0.73

31.05 ± 0.48*

109.28 ± 0.49

5.87 ± 0.05

8.44 ± 0.82

HC +4 weeks treatment

240 mg/kg

135.51 ± 0.51*

101.62 ± 0.98*

20.33 ± 0.79*

26.73 ± 0.47

81.53 ± 0.5*

3.05 ± 0.07*

6.25 ± 0.34*

320 mg/kg

116.63 ± 0,54*

95.06 ± 0.57*

19.02 ± 0.66*

28.35 ± 0.58*

53.02 ± 0.83*

1.87 ± 0.06*

4.59 ± 0.16*

400 mg/kg

106.07 ± 0.69*

85.15 ± 0.64*

16.65 ± 0.38*

34.77 ± 0.6*

36.17 ± 0.34*

0.96 ± 0.04*

3.96 ± 0.15*

HC 4 weeks after treatment

240 mg/kg

130.12 ± 0.11*

98.13 ± 0.30*

18.30 ± 0.70*

27.12 ± 0.17

80.31 ± 0.15*

2.96 ± 0.02*

4.79 ± 0.13*

320 mg/kg

110.22 ± 0,34*

89.16 ± 0.33*

16.12 ± 0.25*

30.22 ± 0.32*

48.22 ± 0.23*

1.59 ± 0.03*

3.64 ± 0.11*

400 mg/kg

99.14 ± 0.44*

79.17 ± 0.24*

14.25 ± 0.31*

36.43 ± 0.21*

33.27 ± 0.14*

0.91 ± 0.02*

2.72 ± 0.12*

HC + Atorvastatin

1 mg/kg

95.23 ± 0.57*

86.84 ± 0.84*

17.27 ± 0.63*

31.05 ± 0.48*

39.06 ± 0.97*

1.26 ± 0.04*

3.29 ± 0.42*

NC rats

69.61 ± 0.92

69.46 ± 0.58

14.39 ± 0.57

30.83 ± 0.39

25.38 ± 0.66

0.83 ± 0.07

2.28 ± 0.07

  1. Data are represented as mean ± standard error of mean, n = 5. One-way ANOVA + LSD test against hypercholesterolemic (HC) rats: *P < 0.05. dH 2 O distilled water, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol, NC normocholesterolemic, T treatment, TC total cholesterol, TG triglyceride, VLDL-c very low density lipoprotein cholesterol