Antinociceptive effect of methanol extract of Dalbergia sissoo leaves in mice

Table 9 Effects of D. sissoo leave extract on involvement of ATP-sensitive K⁺ channel pathway

Treatment	Dose (mg/kg)	Number of writhing	Inhibition (%)
Control	0.1 mL/ mouse	73.4 ± 1.71	–
Glibenclamide (GB)	10	62.3 ± 1.11	15.12
MEDS + GB	100 + 10	42.3 ± 2.07**	42.37
MEDS + GB	200 + 10	35.3 ± 1.45***	51.91
MEDS + GB	400 + 10	24.2 ± 2.02***	67.03

Values are presented as mean ± SEM (n = 5). MEDS Methanolic extract of D. sissoo
*** p < 0.001 compared with the control group (Dunnett’s test)
** p < 0.01 compared with the control group (Dunnett’s test)

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