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Table 9 Effects of D. sissoo leave extract on involvement of ATP-sensitive K+ channel pathway

From: Antinociceptive effect of methanol extract of Dalbergia sissoo leaves in mice

Treatment Dose (mg/kg) Number of writhing Inhibition (%)
Control 0.1 mL/ mouse 73.4 ± 1.71
Glibenclamide (GB) 10 62.3 ± 1.11 15.12
MEDS + GB 100 + 10 42.3 ± 2.07** 42.37
MEDS + GB 200 + 10 35.3 ± 1.45*** 51.91
MEDS + GB 400 + 10 24.2 ± 2.02*** 67.03
  1. Values are presented as mean ± SEM (n = 5). MEDS Methanolic extract of D. sissoo
  2. *** p < 0.001 compared with the control group (Dunnett’s test)
  3. ** p < 0.01 compared with the control group (Dunnett’s test)