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Table 8 Effects of D. sissoo leave extract on involvement of cyclic guanosine monophosphate (cGMP) pathway

From: Antinociceptive effect of methanol extract of Dalbergia sissoo leaves in mice

Treatment Dose (mg/kg) Number of writhing Inhibition (%)
Control 0.1 mL/ mouse 71.74 ± 1.77
Methylene Blue (MB) 20 58.20 ± 2.89*** 18.87
MEDS + MB 100 + 20 37.90 ± 0.96** 47.17
MEDS + MB 200 + 20 26.10 ± 1.69*** 63.62
MEDS + MB 400 + 20 15.90 ± 1.52*** 77.84
  1. Values are presented as mean ± SEM (n = 5). MEDS Methanolic extract of D. sissoo
  2. *** p < 0.001 compared with the control group (Dunnett’s test)
  3. ** p < 0.01 compared with the control group (Dunnett’s test)