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Table 5 Antinociceptive effects of D. sissoo leave extract in formalin-induced nociception

From: Antinociceptive effect of methanol extract of Dalbergia sissoo leaves in mice

Treatment

Dose (mg/kg)

Licking of the hind paw

Early phase (0–5 min)

Inhibition (%)

Late phase (15–30 min)

Inhibition (%)

Control

0.1 mL/ mouse

95.40 ± 1.33

41.80 ± 2.15

Diclofenac sodium

10

27.80 ± 2.73***

70.86

6.60 ± 0.51***

84.21

MEDS

100

66.20 ± 1.98*

30.60

14.60 ± 1.75***

65.05

MEDS

200

52.40 ± 0.87*

45.07

12.00 ± 1.00***

71.29

MEDS

400

34.80 ± 1.20*

63.52

08.20 ± 0.73***

80.38

  1. Values are presented as mean ± SEM (n = 5). MEDS Methanolic extract of D. sissoo
  2. *** p < 0.001 compared with the control group (Dunnett’s test)
  3. * p < 0.05 compared with the control group (Dunnett’s test)