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Table 4 Effect of crude and flavonoids extracts of Rubus ulmifolius on yeast-induced pyrexia in Rats

From: Pharmacological profile of the aerial parts of Rubus ulmifolius Schott

Groups

Rectal Temperature in °C

Normal

Brewer’s yeast

After administration of test samples and standard drug

1sthr

2ndhr

3rdhr

4thhr

GI (Control)

37.36 ± 0.08

39.61 ± 0.03

39.41 ± 0.04 (8.88%)

39.48 ± 0.06 (5.92%)

39.43 ± 0.07 (8.14%)

39.46 ± 0.04 (6.66%)

GII (Paracetamol)

37.46 ± 0.04

39.4 ± 0.06

38.86 ± 0.08 (27.58%)

38.38 ± 0.07 (52.58%)

38 ± 0.05*** (72.41%)

37.7 ± 0.05*** (87.93%)

Ru.Cr

GIII 150 mg

37.13 ± 0.03

39.45 ± 0.24

39.36 ± 0.08 (3.87%)

39.10 ± 0.15 (15.08%)

38.76 ± 0.23 (29.74%)

38.20 ± 0.11* (53.87%)

GIV 300 mg

37.23 ± 0.08

38.90 ± 0.30

38.71 ± 0.08 (11.37%)

38.36 ± 0.34 (32.33%)

37.93 ± 0.42** (58.08%)

37.66 ± 0.38*** (74.25%)

Ru.F

GV 150 mg

37.16 ± 0.08

39.36 ± 0.38

38.84 ± 0.12 (23.63%)

38.71 ± 0.35 (29.54%)

38.53 ± 0.12 (37.72%)

37.87 ± 0.50** (67.72%)

GVI 300 mg

37.26 ± 0.12

39.66 ± 0.20

38.70 ± 0.45 (40%)

38.23 ± 0.08** (59.58%)

37.86 ± 0.18*** (75%)

37.60 ± 0.05*** (85.83%)

  1. All values are taken as mean ± SEM (n = 3), **P < 0.05, ***P < 0.01