Evaluation of the antimycobacterial activity of crude extracts and solvent fractions of selected Ethiopian medicinal plants

Table 2 Antimycobacterial activity of experimental plants using colony count method

Concentration of extract (mg/ml)	CFU/ml
Concentration of extract (mg/ml)	DMSO ƚ	P. stellatum CHCl₃ extract	P. stellatum MeOH extract	O. integrifolia CHCl₃ extract	O. integrifolia MeOH extract	DMSO ǂ	V. amygdalina CHCl₃ extract	C. edulis CHCl₃ extract	P. americana MeOH extract	P. americana acetone extract
2.50	583	0	0	0	0	354	0	0	0	0
1.25	1194	0	0	0	0	476	0	0	72	0
0.625	2944	0	0	0	0	488	62	43	197	84
0.312	4000	0	0	0	150	742	166	168	64	282
0.156	5944	0	100	334	270	800	260	208	103	94
0.078	8444	0	277	566	650	817	242	222	66	89
0.039	9345	0	302	860	1050	871	496	435	94	344
0.019	1122	100	351	360	886	1275	1033	552	89	1028
0.009	12333	100	421	3334	1334	1517	1733	742	80	28
0.005	19861	100	450	3389	3889	958	2013	813	578	1120
0.0024	16944	100	200	3445	6389	1100	2438	1206	698	1249
Mean ± SEM	7519.45 ± 1984.82	36.36*** ± 15.21	191.00*** ± 53.90	1117.00*** ± 447.7	1329.00 *** ± 608.3	854.36 ± 351.01	767.55 ± 269.50	399.00 ± 117.99	185.55 *** ± 69.34	392.50* ± 147.7

Experiments were carried out in triplicate and results are expressed as means of three replicate experiments. ƚ = Solvent CFU for chloroform and methanol extracts of P. stellatum and O. integrifolia; ǂ = Solvent CFU for chloroform extract of V. amygdalina and C. edulis and 80% methanol and acetone extract of P. Americana,; MeOH = methanol. * = α < 0.05, *** = α < 0.001

ISSN: 2662-7671