Skip to main content

Table 1 Effects of testosterone and, aqueous and methanolic extracts of F. asperifolia on body weight variation and relative organ weights of immature normal rats after four weeks of treatment

From: Androgenic effects of aqueous and methanolic extracts of Ficus asperifolia in male Wistar rats

Groups

Body weight (g)

Body weight variation (%)

Relative organ weights (mg/100 g)

Initial

Final

Testes

Epididymis

Vas deferens

Ventral prostate

Seminal vesicles

Distilled water (10 ml/kg b.w.)

120.00 ± 6.4

173.40 ± 8.84

44.43 ± 1.94

1087.85 ± 20.38

232.78 ± 21.60

63.32 ± 5.05

41.37 ± 7.23

186.47 ± 30.51

5% Tween 80 (10 ml/kg b.w.)

118.80 ± 4.35

168.00 ± 6.77

41.51 ± 3.33

1099.65 ± 71.13

231.52 ± 27.78

57.65 ± 5.44

45.63 ± 7.42

145.48 ± 26.45

Testosterone (0.5 mg/kg b.w.)

120.40 ± 5.87

210.20 ± 12.3

74.41 ± 4.59**

416.25 ± 53.92***

197.87 ± 7.31

66.32 ± 1.68

66.59 ± 11.06

484.98 ± 27.42***

F. asperifolia

 Aqueous extract

  100 mg/kg b.w.

121.20 ± 4.03

176.80 ± 7.11

45.81 ± 2.62≠≠

1098.54 ± 77.69≠≠≠

338.34 ± 29.42**≠≠≠

81.64 ± 6.00*≠

76.72 ± 16.10*

273.40 ± 38.99*≠≠≠

  500 mg/kg b.w.

124.80 ± 7.08

187.80 ± 9.49

51.05 ± 4.91≠

1161.92 ± 75.33≠≠≠

310.56 ± 23.81*≠≠

64.34 ± 2.66

64.63 ± 5.09

243.13 ± 19.96≠≠≠

 Methanolic extract

  100 mg/kg b.w.

120.00 ± 6.38

190.60 ± 9.66

60.16 ± 10.40

1189.18 ± 53.47≠≠≠

327.13 ± 24.35*≠≠

70.77 ± 4.27

96.42 ± 11.72**

307.49 ± 28.97**≠≠≠

  500 mg/kg b.w.

123.40 ± 7.81

194.20 ± 6.45

59.95 ± 11.47

1279.15 ± 14.60*≠≠≠

340.21 ± 32.27**≠≠≠

72.76 ± 5.80

99.81 ± 13.00***≠α

308.94 ± 29.35**≠≠≠

  1. All values: Mean ± SEM; Number of rats per group = 5; *p < 0.05; ** p < 0.01; ***p < 0.001 compared to distilled water; ≠ p < 0.05; ≠≠ p < 0.01; ≠≠≠ p < 0.001 compared to testosterone; α p < 0.05 significantly different at equal dose of plant extracts