ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs

Table 1 Composition of viscum, TT and viscum TT extracts

	CDs [mg/mL]	OA [μg/mL]	BA [μg/mL]	ML [ng/mL]	VT [μg/ml]
TT	230	3600	270	/	/
viscum	230	/	/	570	22.13
viscumTT	230	3600	270	570	22.13
CDs	230	/	/	/	/

Represented is the composition of each mistletoe extract, used in the experiments. TT contain mostly oleanolic acid (OA) and betulinic acid (BA) without mistletoe lectin (ML) or viscotoxins (VT). Viscum contains β-cyclodextrins (CDs), ML and VT and does not include OA or BA. ViscumTT is a combination of both single extracts. The concentrations of ML-I as well as OA and BA in each stock solution are shown. The concentrations of ML (for viscum) and OA (for TT) function as marker substances

ISSN: 2662-7671