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Table 4 The effects of XPJY and sertraline on escapes latency in different groups

From: Effect of XingPiJieYu decoction on spatial learning and memory and cAMP-PKA-CREB-BDNF pathway in rat model of depression through chronic unpredictable stress

Groups

Escape latency (s)

Times crossing platform position

Day1

Day2

Day3

Day4

Day5

Control

CUS

CUS + sertraline 10 mg/kg

CUS + XPJY 1.4 g/kg

CUS + XPJY 0.7 g/kg

CUS + XPJY 0.35 g/kg

25.2 ± 8.2

38.8 ± 7.6++

30.5 ± 13.4

28.6 ± 9.3*

33.1 ± 6.8

34.4 ± 14.6

23.3 ± 6.7

32.9 ± 9.2+

27.7 ± 7.3

25.3 ± 9.6

27.7 ± 10.7

28.7 ± 9.8

21.5 ± 5.9

23.5 ± 5.1

20.2 ± 4.4

20.9 ± 5.2

20.0 ± 4.2

19.6 ± 4.5

18.1 ± 4.1

18.9 ± 5.4

17.6 ± 4.3

17.5 ± 7.3

17.8 ± 5.4

18.9 ± 5.0

4.38 ± 1.51

2.13 ± 1.13++

3.63 ± 1.41*

3.88 ± 1.64*

3.13 ± 1.13

2.88 ± 1.46

  1. Note: ++p < 0.01 vs Control group, +p < 0.05 vs Control group; *p < 0.05 vs CUS group