TY - JOUR AU - Ellis, P. M. AU - Coakley, N. AU - Feld, R. AU - Kuruvilla, S. AU - Ung, Y. C. PY - 2015 DA - 2015// TI - Use of the epidermal growth factor receptor inhibitors gefitinib, erlotinib, afatinib, dacomitinib, and icotinib in the treatment of non-small-cell lung cancer: a systematic review JO - Curr Oncol VL - 22 UR - https://doi.org/10.3747/co.22.2566 DO - 10.3747/co.22.2566 ID - Ellis2015 ER - TY - JOUR AU - Sculier, J. P. AU - Berghmans, T. AU - Meert, A. P. PY - 2015 DA - 2015// TI - Advances in target therapy in lung cancer JO - Eur Respir Rev VL - 24 UR - https://doi.org/10.1183/09059180.00011014 DO - 10.1183/09059180.00011014 ID - Sculier2015 ER - TY - STD TI - West H, Oxnard GR, Doebele RC. Acquired resistance to targeted therapies in advanced non-small cell lung cancer: new strategies and new agents. Am Soc Clin Oncol Educ Book. 2013. doi: 10.1200/EdBook_AM.2013.33.e272. ID - ref3 ER - TY - JOUR AU - Linardou, H. AU - Dahabreh, I. J. AU - Kanaloupiti, D. AU - Siannis, F. AU - Bafaloukos, D. AU - Kosmidis, P. AU - Papadimitriou, C. A. AU - Murray, S. PY - 2008 DA - 2008// TI - Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer JO - Lancet Oncol VL - 9 UR - https://doi.org/10.1016/S1470-2045(08)70206-7 DO - 10.1016/S1470-2045(08)70206-7 ID - Linardou2008 ER - TY - JOUR AU - Gontiner, E. AU - Boussouel, N. AU - Terrasse, C. AU - Jannoyer, M. AU - Ménard, M. AU - Thomasset, B. AU - Bourgaud, F. PY - 2000 DA - 2000// TI - Litchi Chinensis fatty acid diversity: occurrence of the unusual cyclopropanoic fatty acids JO - Biochem Soc Trans VL - 28 UR - https://doi.org/10.1042/bst0280578 DO - 10.1042/bst0280578 ID - Gontiner2000 ER - TY - JOUR AU - Li, J. AU - Jiang, Y. PY - 2007 DA - 2007// TI - Litchi flavnoids: isolation, identification and biological activity JO - Molecules VL - 12 UR - https://doi.org/10.3390/12040745 DO - 10.3390/12040745 ID - Li2007 ER - TY - JOUR AU - Huang, F. AU - Zhang, R. AU - Yang, Y. PY - 2014 DA - 2014// TI - Comparison of physicochemical properties and immunomodulatory activity of polysaccharides from fresh and dried litchi pulp JO - Molecules VL - 19 UR - https://doi.org/10.3390/molecules19043909 DO - 10.3390/molecules19043909 ID - Huang2014 ER - TY - JOUR AU - Xu, X. AU - Xie, H. AU - Hao, J. AU - Jiang, Y. AU - Wei, X. PY - 2011 DA - 2011// TI - Flavnoid glycosides from the seeds of Litchi Chinensis JO - J Agric Food Chem VL - 59 UR - https://doi.org/10.1021/jf104387y DO - 10.1021/jf104387y ID - Xu2011 ER - TY - JOUR AU - Xu, X. AU - Xie, H. AU - Wang, Y. AU - Wei, X. PY - 2010 DA - 2010// TI - A-type proanthocyanidins from lychee seeds and their antioxidant and antiviral activities JO - J Agric Food Chem VL - 58 UR - https://doi.org/10.1021/jf1033202 DO - 10.1021/jf1033202 ID - Xu2010 ER - TY - JOUR AU - Zhang, J. Y. AU - Zhang, C. PY - 2015 DA - 2015// TI - Research progress on the antineoplastic pharmacological effects and mechanisms of Litchi seeds JO - Chin Med VL - 6 UR - https://doi.org/10.4236/cm.2015.61003 DO - 10.4236/cm.2015.61003 ID - Zhang2015 ER - TY - JOUR AU - Lin, C. C. AU - Chung, Y. C. AU - Hsu, C. P. PY - 2013 DA - 2013// TI - Anti-cancer potential of Litchi seed extract JO - World J Exp Med VL - 3 ID - Lin2013 ER - TY - JOUR AU - Hsu, C. P. AU - Lin, C. C. AU - Huang, C. C. AU - Lin, Y. H. AU - Chou, J. C. AU - Tsia, Y. T. AU - Su, J. R. AU - Chung, Y. C. PY - 2012 DA - 2012// TI - Induction of apoptosis and cell cycle arrest in human colorectal carcinoma by Litchi seed extract JO - J Biomed Biotechnol VL - 2012 UR - https://doi.org/10.1155/2012/341479 DO - 10.1155/2012/341479 ID - Hsu2012 ER - TY - JOUR AU - Chung, Y. C. AU - Lin, C. C. AU - Chou, C. C. AU - Hsu, C. P. PY - 2010 DA - 2010// TI - The effect of longan seed polyphenols on colorectal carcinoma cells JO - Euro J Clin Invest VL - 40 UR - https://doi.org/10.1111/j.1365-2362.2010.02322.x DO - 10.1111/j.1365-2362.2010.02322.x ID - Chung2010 ER - TY - JOUR AU - Chung, Y. C. AU - Huang, C. C. AU - Chen, C. H. AU - Chiang, H. C. AU - Chen, K. B. AU - Chen, Y. J. AU - Liu, C. L. AU - Chuang, L. T. AU - Liu, M. AU - Hsu, C. P. PY - 2012 DA - 2012// TI - Grape-seed procyanidins inhibit the in vitro growth and invasion of pancreatic carcinoma cells JO - Pancreas VL - 41 UR - https://doi.org/10.1097/MPA.0b013e318229da41 DO - 10.1097/MPA.0b013e318229da41 ID - Chung2012 ER - TY - JOUR AU - Hsu, C. P. AU - Lin, Y. H. AU - Zhou, S. P. AU - Chung, Y. C. AU - Lin, C. C. AU - Wang, S. C. PY - 2010 DA - 2010// TI - Longan flower extract inhibits the growth of colorectal carcinoma JO - Nutri Cancer VL - 62 UR - https://doi.org/10.1080/01635580903305367 DO - 10.1080/01635580903305367 ID - Hsu2010 ER - TY - JOUR AU - Iida, M. AU - Brand, T. M. AU - Campbell, D. A. AU - Starr, M. M. AU - Luthar, N. AU - Traynor, A. M. AU - Wheeler, D. L. PY - 2013 DA - 2013// TI - Targeting AKT with the allosteric AKT inhibitor MK-2206 in non-small cell lung cancer cells with acquired resistance to cetuximab JO - Cancer Biol Ther VL - 14 UR - https://doi.org/10.4161/cbt.24342 DO - 10.4161/cbt.24342 ID - Iida2013 ER - TY - JOUR AU - Roberts, E. C. AU - Shapiro, P. S. AU - Nahreini, T. S. AU - Pages, G. AU - Pouyssegur, J. AU - Ahn, N. G. PY - 2002 DA - 2002// TI - Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis JO - Mol Cell Biol VL - 22 UR - https://doi.org/10.1128/MCB.22.20.7226-7241.2002 DO - 10.1128/MCB.22.20.7226-7241.2002 ID - Roberts2002 ER - TY - JOUR AU - Wright, J. H. AU - Munar, E. AU - Jameson, D. R. AU - Andreassen, P. R. AU - Margolis, R. L. AU - Seger, R. AU - Krebs, E. G. PY - 1999 DA - 1999// TI - Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts JO - Proc Natl Acad Sci U S A VL - 96 UR - https://doi.org/10.1073/pnas.96.20.11335 DO - 10.1073/pnas.96.20.11335 ID - Wright1999 ER - TY - STD TI - Lin YM, Kuo WW, Velmurugan BK, Hsien HH, Hsieh YL, Hsu HH, Tu CC, Bau DT, Viswanadha VP, Huang CY. Helioxanthin suppresses the cross talk of COX-2/PGE2 and EGFR/ERK pathway to inhibit Arecoline-induced Oral Cancer Cell (T28) proliferation and blocks tumor growth in xenografted nude mice. Environ Toxicol. 2015; doi: 10.1002/tox.22204. ID - ref19 ER - TY - JOUR AU - Kim, H. S. AU - Chang, Y. G. AU - Bae, H. J. AU - Eun, J. W. AU - Shen, Q. AU - Park, S. J. AU - Shin, W. C. AU - Lee, E. K. AU - Park, S. AU - Ahn, Y. M. AU - Park, W. S. AU - Lee, J. Y. AU - Nam, S. W. PY - 2014 DA - 2014// TI - Oncogenic potential of CK2α and its regulatory role in EGF-induced HDAC2 expression in human liver cancer JO - FEBS J VL - 281 UR - https://doi.org/10.1111/febs.12652 DO - 10.1111/febs.12652 ID - Kim2014 ER - TY - JOUR AU - Okumura, S. AU - Jänne, P. A. PY - 2014 DA - 2014// TI - Molecular pathways: the basis for rational combination using MEK inhibitors in KRAS-mutant cancers JO - Clin Cancer Res VL - 20 UR - https://doi.org/10.1158/1078-0432.CCR-13-2365 DO - 10.1158/1078-0432.CCR-13-2365 ID - Okumura2014 ER - TY - JOUR AU - Moreno-Layseca, P. AU - Streuli, C. H. PY - 2014 DA - 2014// TI - Signalling pathways linking integrins with cell cycle progression JO - Matrix Biol VL - 34 UR - https://doi.org/10.1016/j.matbio.2013.10.011 DO - 10.1016/j.matbio.2013.10.011 ID - Moreno-Layseca2014 ER - TY - JOUR AU - Kirsammer, G. AU - Strizzi, L. AU - Margaryan, N. V. AU - Gilgur, A. AU - Hyser, M. AU - Atkinson, J. AU - Kirschmann, D. A. AU - Seftor, E. A. AU - Hendrix, M. J. PY - 2014 DA - 2014// TI - Nodal signaling promotes a tumorigenic phenotype in human breast cancer JO - Semin Cancer Biol VL - 29 UR - https://doi.org/10.1016/j.semcancer.2014.07.007 DO - 10.1016/j.semcancer.2014.07.007 ID - Kirsammer2014 ER - TY - JOUR AU - Hlobilková, A. AU - Knillová, J. AU - Bártek, J. AU - Lukás, J. AU - Kolár, Z. PY - 2003 DA - 2003// TI - The mechanism of action of the tumour suppressor gene PTEN JO - Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub VL - 147 UR - https://doi.org/10.5507/bp.2003.003 DO - 10.5507/bp.2003.003 ID - Hlobilková2003 ER - TY - JOUR AU - Chambard, J. C. AU - Lefloch, R. AU - Pouysségur, J. AU - Lenormand, P. PY - 2007 DA - 2007// TI - ERK implication in cell cycle regulation JO - Biochim Biophys Acta VL - 1773 UR - https://doi.org/10.1016/j.bbamcr.2006.11.010 DO - 10.1016/j.bbamcr.2006.11.010 ID - Chambard2007 ER - TY - JOUR AU - Keenan, S. M. AU - Bellone, C. AU - Baldassare, J. J. PY - 2001 DA - 2001// TI - Cyclin-dependent kinase 2 nucleocytoplasmic translocation is regulated by extracellular regulated kinase JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M100409200 DO - 10.1074/jbc.M100409200 ID - Keenan2001 ER - TY - JOUR AU - Sherr, C. J. AU - Roberts, J. M. PY - 1999 DA - 1999// TI - CDK inhibitors: positive and negative regulators of G1-phase progression JO - Genes Dev VL - 13 UR - https://doi.org/10.1101/gad.13.12.1501 DO - 10.1101/gad.13.12.1501 ID - Sherr1999 ER - TY - JOUR AU - Weber, J. D. AU - Raben, D. M. AU - Phillips, P. J. AU - Baldassare, J. J. PY - 1997 DA - 1997// TI - Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase JO - Biochem J VL - 326 UR - https://doi.org/10.1042/bj3260061 DO - 10.1042/bj3260061 ID - Weber1997 ER - TY - JOUR AU - Lavoie, J. N. AU - L’Allemain, G. AU - Brunet, A. AU - Müller, R. AU - Pouysségur, J. PY - 1996 DA - 1996// TI - Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.34.20608 DO - 10.1074/jbc.271.34.20608 ID - Lavoie1996 ER -