Fig. 6

Effects of 4'-O-demethylophiopogonanone E (10) on the mRNA expression of IL-1β (a), IL-6 (b) and iNOS (c) in LPS-induced RAW264.7 macrophages. Cells were pre-treated for 2 h with indicated concentrations of 10 and then stimulated with LPS (final concentration 1 μg/mL) for another 12 h. Data are expressed as mean ± S.D. Of three independent experiments. ## p < 0.01 as compared with the control group, * p < 0.05 and ** p < 0.01 versus the LPS group, △ p < 0.05 and △△ p < 0.01 versus the DXM group