Fig. 4

Effect of OA-F2 on CRP levels in the serum. Values are expressed as difference in Mean ± SE between before (13th day) and after (34th day) treatment; n = 6. ^*** p < 0.001 compared to OAC. ^# p < 0.05, ^### p < 0.001 compared to DICLO. Data were analyzed by One-Way ANOVA followed by Dunnett's multiple comparison test. HC: Healthy control, OAC: Osteoarthritic control, DICLO: Positive control, OA-F2L: OA-F2 at 135 mg/kg b. wt., OA-F2M: OA-F2 at 270 mg/kg b. wt., OA-F2H: OA-F2 at 540 mg/kg b. wt