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Table 5 The inhibitory effects of different concentrations of F2 fraction on the volume of papilloma (mm3) at weeks 15, 18 and 21 in tumor-bearing mice

From: Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer

 

Week 15

 

Week 18

 

Week 21

 

Treatments

Tumor Volume

% Inhibition

Tumor Volume

% Inhibition

Tumor Volume

% Inhibition

Control (DMSO)

83.5 ± 6.0

0

105.3 ± 5.0

0

133.3 ± 6.8

0

10 mg/Kg

59.7 ± 5.3*

28.5

85.5 ± 4.2*

18.8

116.0 ± 3.6*

13.0

50 mg/Kg

44.8 ± 5.7**

46.3

60.6 ± 2.8**

42.5

82.9 ± 3.8**

37.8

200 mg/Kg

34.4 ± 4.2**

58.8

40.0 ± 2.7**

62.0

61.2 ± 3.0**

54.0

  1. Values are mean ± SEM. n = 10
  2. * P < 0.05, ** P < 0.001 vs control