Test substance | Dose (mg/kg) | Body weight | % change | |
---|---|---|---|---|
D0 (g) | D4 (g) | |||
AE | 200 | 30.33 ± 1.93 | 28.28 ± 3.82 | −8.29 ± 9.97 c1,e2,d2 |
400 | 29.83 ± 1.40 | 30.35 ± 1.35 | 1.65 ± 3.53 a1,b1 | |
600 | 29.40 ± 1.69 | 30.76 ± 1.73 | 4.41 ± 2.72 a2,b2 | |
Vehicle | 1 ml | 29.26 ± 1.26 | 27.30 ± 1.10 | −7.18 ± 1.52 |
CQ | 25 | 29.11 ± 1.54 | 30.12 ± 2.03 | 3.21 ± 3.50 |
HE | 200 | 31.33 ± 0.54 | 29.88 ± 2.58 | −5.43 ± 8.30 |
400 | 29.63 ± 1.45 | 30.16 ± 1.32 | 1.73 ± 3.442 a1 | |
600 | 30.41 ± 1.92 | 32.45 ± 2.23 | 6.22 ± 1.02 a3,b2 | |
Vehicle | 1 ml | 29.26 ± 1.26 | 27.30 ± 1.10 | −7.18 ± 1.52 |
CQ | 25 | 29.11 ± 1.54 | 30.12 ± 2.03 | 3.21 ± 3.50 |