TY - JOUR AU - Choy, E. PY - 2012 DA - 2012// TI - Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis JO - Rheumatology VL - 51 UR - https://doi.org/10.1093/rheumatology/kes113 DO - 10.1093/rheumatology/kes113 ID - Choy2012 ER - TY - JOUR AU - McInnes, I. B. AU - Schett, G. PY - 2011 DA - 2011// TI - The pathogenesis of rheumatoid arthritis JO - N Engl J Med VL - 365 UR - https://doi.org/10.1056/NEJMra1004965 DO - 10.1056/NEJMra1004965 ID - McInnes2011 ER - TY - JOUR AU - Bartok, B. AU - Firestein, G. S. PY - 2010 DA - 2010// TI - Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis JO - Immunol Rev VL - 233 UR - https://doi.org/10.1111/j.0105-2896.2009.00859.x DO - 10.1111/j.0105-2896.2009.00859.x ID - Bartok2010 ER - TY - JOUR AU - Lundy, S. K. AU - Sarkar, S. AU - Tesmer, L. A. AU - Fox, D. A. PY - 2007 DA - 2007// TI - Cells of the synovium in rheumatoid arthritis. T lymphocytes JO - Arthritis Res Ther VL - 9 UR - https://doi.org/10.1186/ar2107 DO - 10.1186/ar2107 ID - Lundy2007 ER - TY - JOUR AU - Smolen, J. S. AU - Aletaha, D. AU - Koeller, M. AU - Weisman, M. H. AU - Emery, P. PY - 2007 DA - 2007// TI - New therapies for treatment of rheumatoid arthritis JO - Lancet VL - 370 UR - https://doi.org/10.1016/S0140-6736(07)60784-3 DO - 10.1016/S0140-6736(07)60784-3 ID - Smolen2007 ER - TY - JOUR AU - Smolen, J. S. AU - Steiner, G. PY - 2003 DA - 2003// TI - Therapeutic strategies for rheumatoid arthritis JO - Nat Rev Drug Discov VL - 2 UR - https://doi.org/10.1038/nrd1109 DO - 10.1038/nrd1109 ID - Smolen2003 ER - TY - JOUR AU - Shegarfi, H. AU - Naddafi, F. AU - Mirshafiey, A. PY - 2012 DA - 2012// TI - Natural killer cells and their role in rheumatoid arthritis: friend or foe? JO - Sci World J VL - 2012 UR - https://doi.org/10.1100/2012/491974 DO - 10.1100/2012/491974 ID - Shegarfi2012 ER - TY - JOUR AU - Dalbeth, N. AU - Callan, M. F. PY - 2002 DA - 2002// TI - A subset of natural killer cells is greatly expanded within inflamed joints JO - Arthritis Rheum VL - 46 UR - https://doi.org/10.1002/art.10410 DO - 10.1002/art.10410 ID - Dalbeth2002 ER - TY - JOUR AU - Aramaki, T. AU - Ida, H. AU - Izumi, Y. AU - Fujikawa, K. AU - Huang, M. AU - Arima, K. AU - Tamai, M. AU - Kamachi, M. AU - Nakamura, H. AU - Kawakami, A. PY - 2009 DA - 2009// TI - A significantly impaired natural killer cell activity due to a low activity on a per-cell basis in rheumatoid arthritis JO - Mod Rheumatol VL - 19 UR - https://doi.org/10.3109/s10165-009-0160-6 DO - 10.3109/s10165-009-0160-6 ID - Aramaki2009 ER - TY - JOUR AU - McInnes, I. B. AU - Schett, G. PY - 2007 DA - 2007// TI - Cytokines in the pathogenesis of rheumatoid arthritis JO - Nat Rev Immunol VL - 7 UR - https://doi.org/10.1038/nri2094 DO - 10.1038/nri2094 ID - McInnes2007 ER - TY - JOUR AU - Firestein, G. S. PY - 2003 DA - 2003// TI - Evolving concepts of rheumatoid arthritis JO - Nature VL - 423 UR - https://doi.org/10.1038/nature01661 DO - 10.1038/nature01661 ID - Firestein2003 ER - TY - JOUR AU - Bettelli, E. AU - Carrier, Y. AU - Gao, W. AU - Korn, T. AU - Strom, T. B. AU - Oukka, M. AU - Weiner, H. L. AU - Kuchroo, V. K. PY - 2006 DA - 2006// TI - Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells JO - Nature VL - 441 UR - https://doi.org/10.1038/nature04753 DO - 10.1038/nature04753 ID - Bettelli2006 ER - TY - JOUR AU - Brown, K. D. AU - Claudio, E. AU - Siebenlist, U. PY - 2008 DA - 2008// TI - The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis JO - Arthritis Res Ther VL - 10 UR - https://doi.org/10.1186/ar2457 DO - 10.1186/ar2457 ID - Brown2008 ER - TY - JOUR AU - Heinrich, P. C. AU - Behrmann, I. AU - Muller-Newen, G. AU - Schaper, F. AU - Graeve, L. PY - 1998 DA - 1998// TI - Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway JO - Biochem J VL - 334 UR - https://doi.org/10.1042/bj3340297 DO - 10.1042/bj3340297 ID - Heinrich1998 ER - TY - JOUR AU - Wei Shi, N. T. AU - Jing, X. AU - Lijun, Z. AU - Limin, C. AU - Jinyu, W. PY - 2012 DA - 2012// TI - Clinical study on the treatment of rheumatoid arthritis in active phase with the Lijie capsule JO - Lishizhen Med Mater Med Res VL - 12 ID - Wei Shi2012 ER - TY - JOUR AU - Tang Nong, C. L. AU - Zhang, L. AU - Lin, G. AU - Huang, X. PY - 2006 DA - 2006// TI - Influences of Lijie Capsules on expressions of Fas and FasL genes in lymphocytes in rats with adjuvant arthritis JO - J Beijing Univ Tradit Chin Med VL - 29 ID - Tang Nong2006 ER - TY - JOUR AU - Lou, L. AU - Liu, Y. AU - Zhou, J. AU - Wei, Y. AU - Deng, J. AU - Dong, B. AU - Chai, L. PY - 2015 DA - 2015// TI - Chlorogenic acid and luteolin synergistically inhibit the proliferation of interleukin-1beta-induced fibroblast-like synoviocytes through regulating the activation of NF-kappaB and JAK/STAT-signaling pathways JO - Immunopharmacol Immunotoxicol VL - 37 UR - https://doi.org/10.3109/08923973.2015.1095763 DO - 10.3109/08923973.2015.1095763 ID - Lou2015 ER - TY - JOUR AU - Lou, L. AU - Zhou, J. AU - Liu, Y. AU - Wei, Y. I. AU - Zhao, J. AU - Deng, J. AU - Dong, B. AU - Zhu, L. AU - Wu, A. AU - Yang, Y. PY - 2016 DA - 2016// TI - Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-kappaB signaling pathways JO - Exp Ther Med VL - 11 ID - Lou2016 ER - TY - JOUR AU - Huang, J. AU - Lu, X. Q. AU - Zhang, C. AU - Lu, J. AU - Li, G. Y. AU - Lin, R. C. AU - Wang, J. H. PY - 2013 DA - 2013// TI - Anti-inflammatory ligustilides from Ligusticum chuanxiong Hort JO - Fitoterapia VL - 91 UR - https://doi.org/10.1016/j.fitote.2013.08.013 DO - 10.1016/j.fitote.2013.08.013 ID - Huang2013 ER - TY - JOUR AU - Jia, N. AU - Li, Y. AU - Wu, Y. AU - Xi, M. AU - Hur, G. AU - Zhang, X. AU - Cui, J. AU - Sun, W. AU - Wen, A. PY - 2012 DA - 2012// TI - Comparison of the anti-inflammatory and analgesic effects of Gentiana macrophylla Pall. and Gentiana straminea Maxim., and identification of their active constituents JO - J Ethnopharmacol VL - 144 UR - https://doi.org/10.1016/j.jep.2012.10.004 DO - 10.1016/j.jep.2012.10.004 ID - Jia2012 ER - TY - JOUR AU - Chen, W. P. AU - Wu, L. D. PY - 2014 DA - 2014// TI - Chlorogenic acid suppresses interleukin-1beta-induced inflammatory mediators in human chondrocytes JO - Int J Clin Exp Pathol VL - 7 ID - Chen2014 ER - TY - JOUR AU - Jiang, J. B. AU - Qiu, J. D. AU - Yang, L. H. AU - He, J. P. AU - Smith, G. W. AU - Li, H. Q. PY - 2010 DA - 2010// TI - Therapeutic effects of astragalus polysaccharides on inflammation and synovial apoptosis in rats with adjuvant-induced arthritis JO - Int J Rheum Dis VL - 13 UR - https://doi.org/10.1111/j.1756-185X.2010.01555.x DO - 10.1111/j.1756-185X.2010.01555.x ID - Jiang2010 ER - TY - JOUR AU - Chen, X. P. AU - Li, W. AU - Xiao, X. F. AU - Zhang, L. L. AU - Liu, C. X. PY - 2013 DA - 2013// TI - Phytochemical and pharmacological studies on Radix Angelica sinensis JO - Chin J Nat Med VL - 11 UR - https://doi.org/10.3724/SP.J.1009.2013.00577 DO - 10.3724/SP.J.1009.2013.00577 ID - Chen2013 ER - TY - JOUR AU - Oh, K. O. AU - Kim, S. W. AU - Kim, J. Y. AU - Ko, S. Y. AU - Kim, H. M. AU - Baek, J. H. AU - Ryoo, H. M. AU - Kim, J. K. PY - 2003 DA - 2003// TI - Effect of Rehmannia glutinosa Libosch extracts on bone metabolism JO - Clin Chim Acta VL - 334 UR - https://doi.org/10.1016/S0009-8981(03)00238-9 DO - 10.1016/S0009-8981(03)00238-9 ID - Oh2003 ER - TY - JOUR AU - Sun, G. AU - Li, L. AU - Li, Y. AU - Song, A. PY - 2014 DA - 2014// TI - Study on the digitized and quantified evaluating method for super information characteristics of herbal preparation by infrared spectrum fingerprints JO - Ann Transl Med VL - 2 ID - Sun2014 ER - TY - JOUR AU - Noordzij, M. AU - Dekker, F. W. AU - Zoccali, C. AU - Jager, K. J. PY - 2011 DA - 2011// TI - Sample size calculations JO - Nephron Clin Pract VL - 118 UR - https://doi.org/10.1159/000322830 DO - 10.1159/000322830 ID - Noordzij2011 ER - TY - JOUR AU - Kato, G. AU - Shimizu, Y. AU - Arai, Y. AU - Suzuki, N. AU - Sugamori, Y. AU - Maeda, M. AU - Takahashi, M. AU - Tamura, Y. AU - Wakabayashi, N. AU - Murali, R. PY - 2015 DA - 2015// TI - The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study JO - Arthritis Res Ther VL - 17 UR - https://doi.org/10.1186/s13075-015-0753-8 DO - 10.1186/s13075-015-0753-8 ID - Kato2015 ER - TY - JOUR AU - Hsiao, H. B. AU - Hsieh, C. C. AU - Wu, J. B. AU - Lin, H. AU - Lin, W. C. PY - 2016 DA - 2016// TI - Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses JO - BMC Complement Altern Med VL - 16 UR - https://doi.org/10.1186/s12906-016-1054-8 DO - 10.1186/s12906-016-1054-8 ID - Hsiao2016 ER - TY - JOUR AU - Takahi, K. AU - Hashimoto, J. AU - Hayashida, K. AU - Shi, K. AU - Takano, H. AU - Tsuboi, H. AU - Matsui, Y. AU - Nakase, T. AU - Tomita, T. AU - Ochi, T. PY - 2002 DA - 2002// TI - Early closure of growth plate causes poor growth of long bones in collagen-induced arthritis rats JO - J Musculoskelet Neuronal Interact VL - 2 ID - Takahi2002 ER - TY - JOUR AU - Pan, T. L. AU - Wang, P. W. AU - Huang, C. H. AU - Leu, Y. L. AU - Wu, T. H. AU - Wu, Y. R. AU - You, J. S. PY - 2015 DA - 2015// TI - Herbal formula, Scutellariae radix and Rhei rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a rat model JO - Sci Rep VL - 5 UR - https://doi.org/10.1038/srep11734 DO - 10.1038/srep11734 ID - Pan2015 ER - TY - JOUR AU - Xue, T. AU - Roy, R. PY - 2003 DA - 2003// TI - Studying traditional Chinese medicine JO - Science VL - 300 UR - https://doi.org/10.1126/science.300.5620.740 DO - 10.1126/science.300.5620.740 ID - Xue2003 ER - TY - JOUR AU - Lee, H. J. AU - Seo, H. S. AU - Ryu, J. AU - Yoon, Y. P. AU - Park, S. H. AU - Lee, C. J. PY - 2014 DA - 2014// TI - Luteolin inhibited the gene expression, production and secretion of MUC5AC mucin via regulation of nuclear factor kappa B signaling pathway in human airway epithelial cells JO - Pulm Pharmacol Ther VL - 31 UR - https://doi.org/10.1016/j.pupt.2014.09.008 DO - 10.1016/j.pupt.2014.09.008 ID - Lee2014 ER - TY - JOUR AU - Choi, W. S. AU - Shin, P. G. AU - Lee, J. H. AU - Kim, G. D. PY - 2012 DA - 2012// TI - The regulatory effect of veratric acid on NO production in LPS-stimulated RAW264.7 macrophage cells JO - Cell Immunol VL - 280 UR - https://doi.org/10.1016/j.cellimm.2012.12.007 DO - 10.1016/j.cellimm.2012.12.007 ID - Choi2012 ER - TY - JOUR AU - Wei, S. AU - Chi, H. AU - Kodama, H. AU - Chen, G. PY - 2013 DA - 2013// TI - Anti-inflammatory effect of three iridoids in human neutrophils JO - Nat Prod Res VL - 27 UR - https://doi.org/10.1080/14786419.2012.668687 DO - 10.1080/14786419.2012.668687 ID - Wei2013 ER - TY - JOUR AU - Ni, J. AU - Yang, D. AU - Song, L. AU - Li, C. PY - 2015 DA - 2015// TI - Protective effects of paeoniflorin on alveolar bone resorption and soft-tissue breakdown in experimental periodontitis JO - J Periodontal Res VL - 51 UR - https://doi.org/10.1111/jre.12305 DO - 10.1111/jre.12305 ID - Ni2015 ER - TY - JOUR AU - Yamabe, N. AU - Noh, J. S. AU - Park, C. H. AU - Kang, K. S. AU - Shibahara, N. AU - Tanaka, T. AU - Yokozawa, T. PY - 2010 DA - 2010// TI - Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice JO - Eur J Pharmacol VL - 648 UR - https://doi.org/10.1016/j.ejphar.2010.08.044 DO - 10.1016/j.ejphar.2010.08.044 ID - Yamabe2010 ER - TY - JOUR AU - Mencherini, T. AU - Cau, A. AU - Bianco, G. AU - Della Loggia, R. AU - Aquino, R. P. AU - Autore, G. PY - 2007 DA - 2007// TI - An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties JO - J Pharm Pharmacol VL - 59 UR - https://doi.org/10.1211/jpp.59.6.0016 DO - 10.1211/jpp.59.6.0016 ID - Mencherini2007 ER - TY - JOUR AU - Zhao, L. AU - Ye, J. AU - Wu, G. T. AU - Peng, X. J. AU - Xia, P. F. AU - Ren, Y. PY - 2015 DA - 2015// TI - Gentiopicroside prevents interleukin-1 beta induced inflammation response in rat articular chondrocyte JO - J Ethnopharmacol VL - 172 UR - https://doi.org/10.1016/j.jep.2015.06.031 DO - 10.1016/j.jep.2015.06.031 ID - Zhao2015 ER - TY - JOUR AU - Zhang, W. J. AU - Frei, B. PY - 2015 DA - 2015// TI - Astragaloside IV inhibits NF- kappa B activation and inflammatory gene expression in LPS-treated mice JO - Mediators Inflamm VL - 2015 ID - Zhang2015 ER - TY - JOUR AU - Jing, W. AU - Chunhua, M. AU - Shumin, W. PY - 2015 DA - 2015// TI - Effects of acteoside on lipopolysaccharide-induced inflammation in acute lung injury via regulation of NF-kappaB pathway in vivo and in vitro JO - Toxicol Appl Pharmacol VL - 285 UR - https://doi.org/10.1016/j.taap.2015.04.004 DO - 10.1016/j.taap.2015.04.004 ID - Jing2015 ER - TY - JOUR AU - Chen, N. AU - Wu, Q. AU - Chi, G. AU - Soromou, L. W. AU - Hou, J. AU - Deng, Y. AU - Feng, H. PY - 2013 DA - 2013// TI - Prime-O-glucosylcimifugin attenuates lipopolysaccharide-induced acute lung injury in mice JO - Int Immunopharmacol VL - 16 UR - https://doi.org/10.1016/j.intimp.2013.04.014 DO - 10.1016/j.intimp.2013.04.014 ID - Chen2013 ER - TY - JOUR AU - Moon, L. AU - Ha, Y. M. AU - Jang, H. J. AU - Kim, H. S. AU - Jun, M. S. AU - Kim, Y. M. AU - Lee, Y. S. AU - Lee, D. H. AU - Son, K. H. AU - Kim, H. J. PY - 2011 DA - 2011// TI - Isoimperatorin, cimiside E and 23-O-acetylshengmanol-3-xyloside from Cimicifugae rhizome inhibit TNF-alpha-induced VCAM-1 expression in human endothelial cells: involvement of PPAR-gamma upregulation and PI3K, ERK1/2, and PKC signal pathways JO - J Ethnopharmacol VL - 133 UR - https://doi.org/10.1016/j.jep.2010.10.004 DO - 10.1016/j.jep.2010.10.004 ID - Moon2011 ER - TY - JOUR AU - Mia, M. M. AU - Bank, R. A. PY - 2015 DA - 2015// TI - The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis JO - Cell Tissue Res VL - 363 UR - https://doi.org/10.1007/s00441-015-2285-6 DO - 10.1007/s00441-015-2285-6 ID - Mia2015 ER - TY - JOUR AU - Park, J. S. AU - Lee, H. J. AU - Lee, D. Y. AU - Jo, H. S. AU - Jeong, J. H. AU - Kim, D. H. AU - Nam, D. C. AU - Lee, C. J. AU - Hwang, S. C. PY - 2015 DA - 2015// TI - Chondroprotective Effects of Wogonin in Experimental Models of Osteoarthritis in vitro and in vivo JO - Biomol Ther VL - 23 UR - https://doi.org/10.4062/biomolther.2015.045 DO - 10.4062/biomolther.2015.045 ID - Park2015 ER - TY - JOUR AU - Chen, Y. AU - Lu, N. AU - Ling, Y. AU - Gao, Y. AU - Wang, L. AU - Sun, Y. AU - Qi, Q. AU - Feng, F. AU - Liu, W. AU - Liu, W. PY - 2009 DA - 2009// TI - Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction JO - Toxicology VL - 259 UR - https://doi.org/10.1016/j.tox.2009.01.010 DO - 10.1016/j.tox.2009.01.010 ID - Chen2009 ER - TY - JOUR AU - Li, Y. R. AU - Chen, D. Y. AU - Chu, C. L. AU - Li, S. AU - Chen, Y. K. AU - Wu, C. L. AU - Lin, C. C. PY - 2015 DA - 2015// TI - Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritis JO - J Nutr Biochem VL - 26 UR - https://doi.org/10.1016/j.jnutbio.2015.07.016 DO - 10.1016/j.jnutbio.2015.07.016 ID - Li2015 ER - TY - JOUR AU - Park, J. AU - Kim, S. H. AU - Cho, D. AU - Kim, T. S. PY - 2005 DA - 2005// TI - Formononetin, a phyto-oestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activity JO - Immunology VL - 116 UR - https://doi.org/10.1111/j.1365-2567.2005.02199.x DO - 10.1111/j.1365-2567.2005.02199.x ID - Park2005 ER - TY - JOUR AU - Karmakar, S. AU - Kay, J. AU - Gravallese, E. M. PY - 2010 DA - 2010// TI - Bone damage in rheumatoid arthritis: mechanistic insights and approaches to prevention JO - Rheum Dis Clin North Am VL - 36 UR - https://doi.org/10.1016/j.rdc.2010.03.003 DO - 10.1016/j.rdc.2010.03.003 ID - Karmakar2010 ER - TY - JOUR AU - Conigliaro, P. AU - Scrivo, R. AU - Valesini, G. AU - Perricone, R. PY - 2011 DA - 2011// TI - Emerging role for NK cells in the pathogenesis of inflammatory arthropathies JO - Autoimmun Rev VL - 10 UR - https://doi.org/10.1016/j.autrev.2011.04.017 DO - 10.1016/j.autrev.2011.04.017 ID - Conigliaro2011 ER - TY - JOUR AU - Astry, B. AU - Harberts, E. AU - Moudgil, K. D. PY - 2011 DA - 2011// TI - A cytokine-centric view of the pathogenesis and treatment of autoimmune arthritis JO - J Interferon Cytokine Res VL - 31 UR - https://doi.org/10.1089/jir.2011.0094 DO - 10.1089/jir.2011.0094 ID - Astry2011 ER - TY - JOUR AU - Venkatesha, S. H. AU - Dudics, S. AU - Acharya, B. AU - Moudgil, K. D. PY - 2015 DA - 2015// TI - Cytokine-modulating strategies and newer cytokine targets for arthritis therapy JO - Int J Mol Sci VL - 16 UR - https://doi.org/10.3390/ijms16010887 DO - 10.3390/ijms16010887 ID - Venkatesha2015 ER - TY - JOUR AU - Woods, J. M. AU - Tokuhira, M. AU - Berry, J. C. AU - Katschke, K. J. AU - Kurata, H. AU - Damergis, J. A. AU - Arai, K. AU - Koch, A. E. PY - 1999 DA - 1999// TI - Interleukin-4 adenoviral gene therapy reduces production of inflammatory cytokines and prostaglandin E2 by rheumatoid arthritis synovium ex vivo JO - J Investig Med VL - 47 ID - Woods1999 ER - TY - JOUR AU - Vermeij, E. A. AU - Broeren, M. G. AU - Bennink, M. B. AU - Arntz, O. J. AU - Gjertsson, I. AU - LEMvL, P. AU - Berg, W. B. AU - Koenders, M. I. AU - Loo, F. A. PY - 2015 DA - 2015// TI - Disease-regulated local IL-10 gene therapy diminishes synovitis and cartilage proteoglycan depletion in experimental arthritis JO - Ann Rheum Dis VL - 74 UR - https://doi.org/10.1136/annrheumdis-2014-205223 DO - 10.1136/annrheumdis-2014-205223 ID - Vermeij2015 ER - TY - JOUR AU - Firestein, G. S. PY - 2004 DA - 2004// TI - NF-kappaB: Holy Grail for rheumatoid arthritis? JO - Arthritis Rheum VL - 50 UR - https://doi.org/10.1002/art.20468 DO - 10.1002/art.20468 ID - Firestein2004 ER - TY - JOUR AU - Simmonds, R. E. AU - Foxwell, B. M. PY - 2008 DA - 2008// TI - Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation JO - Rheumatology VL - 47 UR - https://doi.org/10.1093/rheumatology/kem298 DO - 10.1093/rheumatology/kem298 ID - Simmonds2008 ER - TY - JOUR AU - Alghasham, A. AU - Rasheed, Z. PY - 2014 DA - 2014// TI - Therapeutic targets for rheumatoid arthritis: Progress and promises JO - Autoimmunity VL - 47 UR - https://doi.org/10.3109/08916934.2013.873413 DO - 10.3109/08916934.2013.873413 ID - Alghasham2014 ER - TY - JOUR AU - O’Brien, C. A. AU - Gubrij, I. AU - Lin, S. C. AU - Saylors, R. L. AU - Manolagas, S. C. PY - 1999 DA - 1999// TI - STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.27.19301 DO - 10.1074/jbc.274.27.19301 ID - O’Brien1999 ER - TY - JOUR AU - Wiacek, R. AU - Kolossa, K. AU - Jankowski, T. AU - Jeka, S. AU - Karmowski, A. AU - Karmowski, M. AU - Gworys, B. PY - 2012 DA - 2012// TI - The efficacy and safety of leflunomide in patients with active rheumatoid arthritis JO - Adv Clin Exp Med VL - 21 ID - Wiacek2012 ER - TY - JOUR AU - Bilasy, S. E. AU - Essawy, S. S. AU - Mandour, M. F. AU - Ali, E. A. AU - Zaitone, S. A. PY - 2015 DA - 2015// TI - Myelosuppressive and hepatotoxic potential of leflunomide and methotrexate combination in a rat model of rheumatoid arthritis JO - Pharmacol Rep VL - 67 UR - https://doi.org/10.1016/j.pharep.2014.08.009 DO - 10.1016/j.pharep.2014.08.009 ID - Bilasy2015 ER -