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Table 4 Acetic acid induced writhing response of pure compounds

From: Sesquiterpene lactone! a promising antioxidant, anticancer and moderate antinociceptive agent from Artemisia macrocephala jacquem

Treatment/Dose

Number of writhing

% inhibition

Control (2% Tween 80)

69.75 ± 1.45

---

Diclofenac sodium (10 mg)

11.65 ± 2.02

83.29

Ism-1 25 mg

50 mgs

54.66 ± 1.20*

21.63

32.35 ± 1.35**

53.62

  1. All the values were expressed as mean ± SEM (n = 6). * P < 0.1, ** P < 0.01 when compared to control group (one way ANOVA followed by Dunnetts: compare all vs control test)