Table 2 The data of top five interaction networks of global targets
From: Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging
Targets in network | Score | Top related Bio Functions and Diseases |
|---|---|---|
ALB, APOB, ATF2, AUH, BCL2, CD40LG, CREB1, CUTA, DDIT3, ELANE, IL6, and other 62 targets | 38 | Cell Death and Survial, Cardiovascular Disease, Gene Expression |
ALOX5, CAV1, CCND1, CDK2, CDK4, CRYZ, CTNNB1, EDN1, EGR1, ESR2, FGF2, and other 47 targets | 27 | Cancer, Organismal Injury and Abnormalities, Cellular Development |
CSD2, DBI, DUOX2, F3, HMOX1, ICAM1, IL4, IL10, IL13, MAOA, MIOX, NOS2, and other 39 targets | 26 | Free Radical Scavenging, Cell to Cell Signaling and Interaction, Cardiovascular Disease |
APP, AR, CASO3, CDKN1A, CXCL8, EGF, FASLG, FN1, HIF1A, IL2, ITGAM, MAPK1, and other 86 targets | 25 | Gene Expression, Cell Death and Survial, Cancer |
ACTA2, ATPC1, BTK, CAPN1, CCL20, CTSB, IL1A, ITGAL, ITGB1, KCNMA1, TP53, and other 106 targets | 22 | Cellular Growth and Proliferation, Connective Tissue Development |