From: Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging
Herbal names (Latin) | Hepatorenal toxicity | Effect | Molecular ingredients (CAS number) | Targets |
---|---|---|---|---|
Ba ji tian (Radix Morindae officinalis) | None | tonifying kidney-Yang | Aascorbic acid (CAS:1972-08-3) | PTGER3, TGFA, VEGFA, FTMT, SLC11A2, and other 42 targets |
Ci wu jia (Radix seu Caulis et Folium Acanthopana) | None | tonifying kidney-Yang | Sesamin (CAS:607-80-7) | NOS3, NOX1, UGT1A1, CYP2B6, CCND1, and other 12 targets |
Du zhong (Cortex Eucommiae) | None | tonifying kidney-Yang | Aucubin (CAS:479-98-1) | BCL2, BAX, TNF, IL6, RELA, NFKBIA, and other 27 targets |
Bu gu zhi (Fructus Psoraleae) | long-term risks of causing kidney disease | tonifying kidney-Yang | Angelicin (CAS:523-50-2) | CYP1A1, ESR1, ESR2, ESTRB, NR3A2, and other 27 targets |
Di huang (Radix Rehmanniae) | None | tonifying kidney-Yin | Catalpol (CAS:2415-24-9) | NOS2, SOD1, CASP3, BCL2, ICAM1, and other 14 targets |
Nv zhen (Radix Ligustri lucidi) | None | tonifying kidney-Yin | Ursolic acid (CAS:77-52-1) | JUN, PTGS2, ACHE, MMP9, RELA, and other 39 targets |
Sang shen (Fructus Mori) | None | tonifying kidney-Yin | Morin (CAS:480-16-0) | XDH, PIP4K2A, ALOX5, CD36, BATF3, and other 58 targets |
Gou qi zi (Fructus Lycii) | None | tonifying kidney-Yin | Beta-carotene (CAS:7235-40-7) | CYP3A4, Cyp2b1, CYP1A2, HMOX1, ALB, and other 77 targets |