Fig. 9From: Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-κB activation and MAPK phosphorylationRepresentative immunohistochemical profiles of COX-2 and iNOS on the paw skins. Note that marked increases of COX-2 (a)- and iNOS (b)-positive cells were detected on the epithelium and dermis of the dorsum and ventrum pedis skin tissues in CA rats compared with normal rats, respectively. However, these increases of epidermal and dermal COX-2- and iNOS-immunolabelled cells were effectively inhibited by treatment with dexamethasone and were also dose-dependently affected by treatment with CBTE at two different dosages: 0.3 and 1.0 g/kg. Immunoreactive cells were stained using ABC methods where a = Normal; b = Carrageenan (CA); c = CA and dexamethasone; d = CA and CBTE 0.3 g/kg; e = CA and CBTE 1.0 g/kg. Scale bars = 60 μm. CBTE, Cheongsangbangpung-tang extract; DEXA, dexamethasoneBack to article page