Table 1 Effect of Lepidium sativum extract on liver and oxidative stress markers in D-GalN/LPS–induced hepatotoxicity

AST U/L

75.80 ± 1.04

213.52 ± 2.59

93.95 ± 0.86

194.28 ± 1.32

126.25 ± 1.62

ALT U/L

33.94 ± 0.98

95.96 ± 1.21

52.39 ± 1.20

82.93 ± 1.61

60.96 ± 1.56

ALP U/L

81.09 ± 1.80

180.86 ± 3.38

94.07 ± 2.03

150.10 ± 2.58

103.76 ± 1.30

Bilurubine plasma mg/dL

0.72 ± 0.01

1.01 ± 0.01

0.69 ± 0.01

0.92 ± 0.012

0.70 ± 0.01

γ-GGT

1.26 ± 0.06

3.12 ± 0.14

1.70 ± 0.04

2.49 ± 0.04

2.01 ± 0.08

CAT U/mg

45.09 ± 1.07

20.98 ± 1.06

39.63 ± 1.63

24.43 ± 1.22

34.18 ± 1.01

GSH nmol/mg

1.17 ± 0.02

0.46 ± 0.02

0.98 ± 0.02

0.71 ± 0.01

0.86 ± 0.02

MDA nmol/minute/mg

3.20 ± 0.10

9.80 ± 0.23

3.95 ± 0.16

7.60 ± 0.18

6.36 ± 0.14

SOD U/mg protein

22.24 ± 0.41

10.53 ± 0.35

20.49 ± 0.85

17.35 ± 0.60

19.57 ± 0.54