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Table 1 Effect of Lepidium sativum extract on liver and oxidative stress markers in D-GalN/LPS–induced hepatotoxicity

From: Hepatoprotective activity of Lepidium sativum seeds against D-galactosamine/lipopolysaccharide induced hepatotoxicity in animal model

Serum Control D-GalN/LPS Silymarin D-GalN/LPS+ LSEE 150 mg/kg D-GalN/LPS+ LSEE 300 mg/kg
AST U/L 75.80 ± 1.04 213.52 ± 2.59 93.95 ± 0.86 194.28 ± 1.32 126.25 ± 1.62
ALT U/L 33.94 ± 0.98 95.96 ± 1.21 52.39 ± 1.20 82.93 ± 1.61 60.96 ± 1.56
ALP U/L 81.09 ± 1.80 180.86 ± 3.38 94.07 ± 2.03 150.10 ± 2.58 103.76 ± 1.30
Bilurubine plasma mg/dL 0.72 ± 0.01 1.01 ± 0.01 0.69 ± 0.01 0.92 ± 0.012 0.70 ± 0.01
γ-GGT 1.26 ± 0.06 3.12 ± 0.14 1.70 ± 0.04 2.49 ± 0.04 2.01 ± 0.08
CAT U/mg 45.09 ± 1.07 20.98 ± 1.06 39.63 ± 1.63 24.43 ± 1.22 34.18 ± 1.01
GSH nmol/mg 1.17 ± 0.02 0.46 ± 0.02 0.98 ± 0.02 0.71 ± 0.01 0.86 ± 0.02
MDA nmol/minute/mg 3.20 ± 0.10 9.80 ± 0.23 3.95 ± 0.16 7.60 ± 0.18 6.36 ± 0.14
SOD U/mg protein 22.24 ± 0.41 10.53 ± 0.35 20.49 ± 0.85 17.35 ± 0.60 19.57 ± 0.54
  1. Data presented as mean ± SEM