Skip to main content
Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Anti-inflammatory and burn injury wound healing properties of the shell of Haliotis diversicolor

Fig. 5

Histological evaluation of burn wound healing effect of SJM. a Paraffin wax tissue sections were stained with hematoxylin and erosin stain to observe the tissues of the burn wounds. Three days after the injury, hair follicle shedding and epidermis thickening were observed in each group, and the number of cells near the epidermis markedly decrased. After 7 days, the hair follicles of each group disappeared. Scarring was obervsed in the burn + SJM-L group, and the burn + SJM-H group exhibited collagen proliferation. After 14 days, the burn + untreated and burn + vehicle groups did not form the epidermis, whereas that of the burn + SJM-L group had begun to form, and a large amount of collagen was observed in this group. The burn + SJM-H group had already devleoped a complete epidermal layer along with a high deposition of collagen fibers. After 28 days, the burn + untreated group exhibited an incomplete epidermal structure, and granulation tissues were still observed. The burn + vehicle group had already grown a thicker epidermis compared with the injury group, but its hair follicles did not appear. The burn + SJM-L and burn + SJM-H groups not only exhibited complete epidermis but also large amounts of hair follicles, and their tissue fibers were neatly arranged. b Observing the magnified image of the corium layer revealed that after 7 and 14 days, the SJM-treated groups exhibited reduced neutrophil infiltration. Scales for (a) and (b) are 500 μm and 50 μm, respectively. EP, epithelial layer. indicates hair follicle; ▲ indicates neutrophil infiltration; arrow indicates collagen fiber

Back to article page