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Table 2 Effect of administration of Melastoma malabathricum Linn. (MM) on the scores of histopathological changes in CFA induced arthritic group rats

From: Melastoma malabathricum Linn attenuates complete freund’s adjuvant-induced chronic inflammation in Wistar rats via inflammation response

S. No Histological changes Groups
   AC AC + MM (100 mg/kg) AC + MM (250 mg/kg) AC + MM (500 mg/kg) AC + Indo (10 mg/kg)
1 Synovial proliferation
  Grade 0 - - - 2 1
  Grade 1 - - - - 1
  Grade 2 - 2 2 2 2
  Grade 3 5 2 1 - -
  Total 15 10 7 4 5
  mean 3 2.5 2.3 1 1.25
2 Cartilage erosion
  Grade 0 - - 2 4 3
  Grade 1 - 2 2 1 1
  Grade 2 2 1 - - -
  Grade 3 3 - - - -
  Total 13 4 2 1 1
  mean 2.6 1.33 0.50 0.20 0.25
3 Cellular infiltration
  Grade 0 - - - 3 3
  Grade 1 - 1 2 2 1
  Grade 2 - 2 2 1 2
  Grade 3 5 1 - - -
  Total 15 10 6 4 5
  mean 3 2.5 1.5 0.67 0.84