Skip to main content

Table 1 Effect of administration of Melastoma malabathricum Linn. (MM) (28 days) on biochemical and hematological parameters in Wistar rats (Male and Female)

From: Melastoma malabathricum Linn attenuates complete freund’s adjuvant-induced chronic inflammation in Wistar rats via inflammation response

S. No Parameters Normal control MM (500 mg/kg, b.w.) MM (1000 mg/kg, b.w.) MM (2000 mg/kg, b.w.)
Male Female Male Female Male Female Male Female
General effect
1 Body Weight (gm) 189.5 ± 8.34 156.2 ± 6.43 176.3 ± 6.34 145.3 ± 8.23 198.3 ± 9.76 151.2 ± 8.32 201.2 ± 11.34 161.3 ± 8.49
2 Water Intake (mL) 102 63 83 65 94 71 104 84
3 Food Intake (gm) 52 44 32 22 44 32 54 46
Hematology
1 RBC (106/cu mm) 6.43 ± 1.21 5.11 ± 1.02 5.98 ± 1.04 5.08 ± 0.95 6.87 ± 1.65 5.21 ± 1.43 7.65 ± 1.76 5.98 ± 1.09
2 WBC (103/cu mm3) 8.99 ± 1.43 7.21 ± 1.84 11.2 ± 1.65 9.43 ± 1.54 10.33 ± 1.64 8.65 ± 1.65 9.01 ± 1.59 7.43 ± 1.94
3 Hb (g dL−1) 13.01 ± 2.03 12.02 ± 2.21 12.54 ± 11.45 11.73 ± 1.98 13.06 ± 2.53 12.32 ± 2.04 14.03 ± 2.83 12.98 ± 2.47
4 Platelet (105/cu mm) 4.01 ± 0.73 3.83 ± 0.49 6 ± 2.01 5.87 ± 1.84 5.21 ± 1.03 5.01 ± 1.13 4.06 ± 0.94 3.78 ± 0.73
5 Eosinophils (mm3) 796 ± 293 498 ± 165 598 ± 384 398 ± 194 654 ± 403 432 ± 214 731 ± 421 489 ± 283
6 Lymphocyte (mm3) 3990 ± 850 2983 ± 594 4350 ± 1039 3214 ± 843 4256 ± 989 3103 ± 784 4013 ± 985 3023 ± 775
7 Neutrophils (mm3) 1596 ± 748 1374 ± 398 1698 ± 983 1485 ± 748 1602 ± 894 1398 ± 738 1545 ± 938 1367 ± 738
Biochemical
1 ALP (UL−1) 221 ± 21.83 209 ± 19.3 298 ± 31.78 285.2 ± 27.31 276.23 ± 24.54 244.5 ± 21.6 234 ± 24.5 213 ± 21.3
2 ALT (UL−1) 61.3 ± 2.34 50.32 ± 2.56 ± ± ± ± ± ±
3 AST (UL−1) 103.2 ± 7.65 80.1 ± 7.87 90.3 ± 6.65 71.3 ± 8.76 95.6 ± 8.65 76.4 ± 7.54 102.3 ± 5.65 79.5 ± 6.87
4 Bilirubin (mg dL−1) 0.52 ± 0.09 0.36 ± 0.07 0.68 ± 0.08 0.43 ± 0.06 0.62 ± 0.06 0.41 ± 0.07 0.55 ± 0.08 0.40 ± 0.05
5 Creatinine (mg dL−1) 0.71 ± 0.43 0.52 ± 0.11 0.86 ± 0.22 0.64 ± 0.15 0.79 ± 0.14 0.58 ± 0.17 0.72 ± 0.21 0.54 ± 0.14
6 Urea (mg dL−1) 36 ± 3.21 26 ± 2.65 41.3 ± 4.54 35.1 ± 3.43 39.3 ± 3.54 32.1 ± 2.45 36.2 ± 4.32 28.5 ± 3.34
7 Cholesterol (mg dL−1) 71.3 ± 1.76 72.5 ± 1.54 82.6 ± 2.33 85.6 ± 3.46 79.6 ± 2.45 83.5 ± 3.43 75.3 ± 4.32 78.4 ± 3.45
8 Triglyceride (mg dL−1) 74.5 ± 1.87 86.7 ± 1.65 88.3 ± 1.76 89.6 ± 1.45 92.2 ± 2.43 93.3 ± 3.21 90.32 ± 2.32 92.3 ± 3.24
9 HDL (mg dL−1) 26.4 ± 1.41 20.6 ± 1.23 28.7 ± 2.73 22.4 ± 1.54 26.1 ± 1.83 21.3 ± 2.65 25.3 ± 2.43 20.3 ± 1.93
10 LDL (mg dL−1) 37.1 ± 1.23 49.83 ± 1.65 51.79 ± 2.13 60.73 ± 1.94 53.69 ± 1.86 61.91 ± 2.01 49.81 ± 1.28 58.01 ± 1.98
11 VLDL (mg dL−1) 14.9 ± 1.34 17.34 ± 1.67 17.66 ± 1.98 17.92 ± 1.56 18.44 ± 1.45 18.66 ± 1.76 18.06 ± 1.34 18.46 ± 1.54