Animal group | Dose (mg/kg-BW) | PT (s) | APTT (s) | N |
---|
Normal | N.D. | 13.2 ± 2.3 | 26.2 ± 4.1 | 8 |
WIB-801CE | 200 | 17.7 ± 4.9NS | 26.3 ± 3.9NS | 8 |
 | 400 | 16.8 ± 3.2NS | 26.0 ± 3.9NS | 8 |
Warfarin | 1 | ∞ | ∞ | 6 |
- The results were expressed as the mean ± standard deviation (n = 8 or 6). ∞, no coagulation; NS not significant versus normal; N.D normal diet, N number of tested rats; BW body weight, PT prothrombin time, APTT activated partial thromboplastin time s, second