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Table 2 Ex vivo effects of WIB-801CE-administration on blood coagulation

From: Antiplatelet and antithrombotic effects of cordycepin-enriched WIB-801CE from Cordyceps militaris ex vivo, in vivo, and in vitro

Animal group

Dose (mg/kg-BW)

PT (s)

APTT (s)

N

Normal

N.D.

13.2 ± 2.3

26.2 ± 4.1

8

WIB-801CE

200

17.7 ± 4.9NS

26.3 ± 3.9NS

8

 

400

16.8 ± 3.2NS

26.0 ± 3.9NS

8

Warfarin

1

∞

∞

6

  1. The results were expressed as the mean ± standard deviation (n = 8 or 6). ∞, no coagulation; NS not significant versus normal; N.D normal diet, N number of tested rats; BW body weight, PT prothrombin time, APTT activated partial thromboplastin time s, second