Antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of organic and aqueous extracts of Hopea odorata leaves and in silico PASS prediction of its isolated compounds

Table 6 In vitro clot lysis activity of H. odorata extracts and Streptokinase on human and mice blood

Drug/Extracts	% of clot lysis for human blood	P value (two-tailed) when compared to negative control	% of clot lysis for mice blood	P value (two-tailed) when compared to negative control
H₂O	06.80 ± 1.38	-	9.06 ± 1.76
SK	76.00 ± 1.13^c	P < 0.001	88.25 ± 1.42^c	P < 0.001
MEHO	52.88 ± 4.1^c	P < 0.001	61.34 ± 2.23^c	P < 0.001
EEHO	24.92 ± 2.44^a	P < 0.05	29.16 ± 2.58^c	P < 0.001
AEHO	38.25 ± 2.25^c	P < 0.001	44.48 ± 2.04^b	P < 0.01

Values are mean ± SEM for 20 volunteers. Data for the effective clot lysis percentage by extracts, positive control (streptokinase) and normal control (distilled water) were processed by paired t-test analysis using Statistical package for social Science (SPSS for windows, version 21.0, IBM Corporation, New York, USA) followed by Dunnet test. ^{a, b} & ^c superscript letters are statistically significant to each other. Values with P < 0.05 are considered as statistically significant

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