Antidiabetic and hypolipidemic activities of hydroethanolic root extract of Uvaria chamae in streptozotocin induced diabetic albino rats

Table 3 Effect of Uvaria chamae on other biochemical parameters on the 8^th Day

Parameter	Group I	Group II	GroupIII	GroupIV	GroupV	Group VI
Protein (g/L)	34.9 ± 0.1	25.7 ± 0.9	20.0 ± 2.3*	35.0 ± 1.2	23.7 ± 0.3	15.0 ± 2.0*
ALB (mg/dl)	43.9 ± 0.3	25.3 ± 1.5*	16.3 ± 1.5*	37.3 ± 0.9	27.0 ± 0.6	33.3 ± 1.2
Creatinine (mg/dl)	0.6 ± 0.01	1.0 ± 0.03	1.0 ± 0.1	1.03 ± 0.2	0.8 ± 0.1	1.13 ± 0.1*
Urea mg/dl	27.7 ± 0.9	56.0 ± 0.6*	64.0 ± 0.6*	43.3 ± 0.9*	31.0 ± 0.6	46.3 ± 2.3*
AST (U/L)	12.6 ± 0.2	27.2 ± 0.2*	13.3 ± 2.2	16.3 ± 0.3	13.8 ± 0.2	31.1 ± 1.8*
ALT (U/L)	10.8 ± 0.5	22.3 ± 1.3*	11.3 ± 2.2	14.8 ± 0.4	12.8 ± 0.4	27.7 ± 0.7*
ALP (U/L)	13.0 ± 0.3	30.7 ± 0.7*	14.7 ± 2.3	23.7 ± 5.7	16.7 ± 1.2	17.8 ± 0.03

*Significant difference (p < 0.05; n = 5) between the Mean ± SEM of test group vs. control. Group I = (control) Normal rats received 0.5 ml (2% solution) of acacia, II = diabetic rats treated with insulin 0.5I.U/kg, III = diabetic rats treated with 400 mg/kg extract, IV = diabetic rats treated with 250 mg/kg extract, V = diabetic rats treated with 100 mg/kg extract, VI = diabetic rats untreated

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