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Table 10 Effect of FOM on antioxidant enzyme activities in acetaminophen induced hepatotoxicity in rats

From: Hepatoprotective potential of Fagonia olivieri DC. against acetaminophen induced toxicity in rat

Treatment (mg/kg bw)

Catalase (U/mg protein)

SOD (U/mg protein)

GSH-Px (nM/min/mg protein)

GR (nM/min/mg protein)

Control (Saline)

5.85 ± 0.13c

4.23 ± 0.22d

114.75 ± 0.97c

127.53 ± 1.90d

AMP 750

2.44 ± 0.04a

1.18 ± 0.25a

69.82 ± 0.20a

75.82 ± 1.65a

AMP + Sily 50

5.68 ± 0.21c

4.32 ± 0.12d

116.14 ± 0.31c

125.31 ± 2.29c

AMP + FOM 200

3.95 ± 0.02b

2.82 ± 0.10b

81.52 ± 1.25b

97.25 ± 1.85b

AMP + FOM 400

5.71 ± 0.15c

3.78 ± 0.57c

110.59 ± 2.18c

116.84 ± 1.39c

FOM 400

5.89 ± 0.43c

4.27 ± 0.49d

118.72 ± 0.66c

129.58 ± 1.75d

  1. Mean ± SEM (06). Means with different superscript letters (a-d) within the column indicate significant difference (p <0.05). AMP, acetaminophen; FOM, F. olivieri methanol extract