Pharmacologically active flavonoids from the anticancer, antioxidant and antimicrobial extracts of Cassia angustifolia Vahl

Ahmed, Shabina Ishtiaq; Hayat, Muhammad Qasim; Tahir, Muhammad; Mansoor, Qaisar; Ismail, Muhammad; Keck, Kristen; Bates, Robert B.

doi:10.1186/s12906-016-1443-z

BMC Complementary Medicine and Therapies

Table 1 Zone of inhibition of C. angustifolia extracts against pathogenic bacterial and fungal strains

From: Pharmacologically active flavonoids from the anticancer, antioxidant and antimicrobial extracts of Cassia angustifolia Vahl

Microrganisms	Extracts	Zones of Inhibition (mm)
Microrganisms	Extracts	1.25 mg/mL	2.5 mg/mL	5 mg/mL	10 mg/mL
Acinetobacter junii	Methanol	0.0 ± 0.0	0.0 ± 0.0	7.5 ± 0.1**	10 ± 0.2**
	Acetone	0.0 ± 0.0	0.0 ± 0.0	7.9 ± 0.1**	9.5 ± 0.1**
	Ethyl acetate	0.0 ± 0.0	8.0 ± 0.2**	10.5 ± 0.2**	11 ± 0.36**
	Ethanol	0.0 ± 0.0	0.0 ± 0.0	8.0 ± 0.36**	10 ± 0.2**
	Aqueous	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
Serratia mercescens	Methanol	8.5 ± 0.2**	8.8 ± 0.3**	10.8 ± 0.26*	11.6 ± 0.2**
	Acetone	9.5 ± 0.36**	9.7 ± 0.17**	10.5 ± 0.60*	12.8 ± 1**
	Ethyl acetate	10.5 ± 0.26*	10.8 ± 0.1**	11.6 ± 1.2*	12.5 ± 1.1*
	Ethanol	9.0 ± 0.60**	10.0 ± 0.17**	12.1 ± .95*	13.3 ± 0.51**
	Aqueous	7.3 ± 0.33**	7.8 ± 0.57**	9.0 ± 0.60**	10.0 ± 0.20**
Enterobacter cloacae	Methanol	7.3 ± 0.26**	7.5 ± 0.20**	8.6 ± 0.36**	10.6 ± 0.20**
	Acetone	0.0 ± 0.0	0.0 ± 0.0	7.5 ± 0.3**	8.5 ± 0.1**
	Ethyl acetate	7.8 ± 0.78*	8.5 ± 0.1**	10.5 ± 0.26**	12.5 ± 0.50**
	Ethanol	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
	Aqueous	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
Pseudomonas aeruginosa	Methanol	7.5 ± 0.20**	8.5 ± 0.1**	10.0 ± 0.20**	12.1 ± 0.43**
	Acetone	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
	Ethyl acetate	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
	Ethanol	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
	Aqueous	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
Salmonella typhi	Methanol	7.8 ± 0.3**	8.8 ± 0.52**	10.8 ± 0.65**	12.17 ± 0.43**
	Acetone	7.1 ± 0.6*	7.8 ± 0.30**	8.2 ± 0.36**	8.9 ± 0.43**
	Ethyl acetate	8.8 ± 0.28**	9.3 ± 0.45**	10.0 ± 0.20**	12.5 ± 0.62**
	Ethanol	7.1 ± 0.26**	8.0 ± 0.34**	10.5 ± 0.50**	11.8 ± 0.40**
	Aqueous	7.6 ± 0.40**	8.8 ± 0.40**	9.5 ± 0.43**	10.0 ± 0.34**
Candida albicans	Methanol	8.5 ± 0.30**	10.5 ± 0.78**	11.5 ± 0.36**	12.0 ± 0.8**
	Acetone	10 ± 0.34**	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
	Ethyl acetate	9.0 ± 0.20**	9.5 ± 0.51**	10 ± 0.20**	0.0 ± 0.0
	Ethanol	10.0 ± 0.1**	10.8 ± 0.40**	11.0 ± 1.3*	11.3 ± 0.55**
	Aqueous	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0

Each value represents the mean ± standard deviation of three replicates (n = 3)
(*), and (**), significant at level P ≤ 0.01 and 0.001, respectively

Back to article page

ISSN: 2662-7671

Contact us

Submission enquiries: bmccomplementarymedicineandtherapies@biomedcentral.com
General enquiries: ORSupport@springernature.com