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Table 5 Effects of the aqueous extract of V. heterophylla on the serum parameters

From: Diuretic and antioxidant activities of the aqueous extract of leaves of Vepris heterophylla (Engl.) R. Let (Rutaceae) in rats

Drugs (mg/kg) glucose (mg/dl) Creatinine (mg/dl) Urea (mg/dl) Albumin (g/l) Aldosterone (pg/mL) Na+ (méq.L–1) K+ (méq.L–1) POSM (mosmol/kg)
Control 89,22 ± 2,11 0,55 ± 0,22 21,12 ± 0,38 42,52 ± 1,14 279,34 ± 13,41 1,76 ± 0,43 1,80 ± 0,77 269,11 ± 11,11
Extract 150 90,45 ± 2,34* 0,62 ± 0,45* 22,38 ± 1,11 43,66 ± 1,22 281,22 ± 21,55 6,42 ± 0,75*** 3,79 ± 1,66*** 277,52 ± 12,33**
200 91,66 ± 4,33* 0,66 ± 0,57** 23,89 ± 2,44** 44,72 ± 2,34** 287,57 ± 12,12** 8,22 ± 1,56*** 4,78 ± 2,52*** 279,66 ± 21,42***
250 95,88 ± 3,41* 0,87 ± 0,29*** 26,77 ± 2,33*** 44,65 ± 3,67*** 306,11 ± 32,22*** 10,88 ± 1,56*** 5,74 ± 1,16*** 285,33 ± 23,43***
Furosemide (5 mg/kg) 95,67 ± 4,98* 0,75 ± 0,23*** 24,56 ± 3,33** 44,43 ± 1,63** 302,53 ± 23,35*** 11,22 ± 1,42*** 6,73 ± 1,34*** 284,21 ± 24,14***
HCTZ (10 mg/kg) 94,22 ± 3,55* 0,74 ± 0,61*** 26,22 ± 1,13*** 43,66 ± 1,32*** 292,88 ± 11,23*** 7,31 ± 1,72*** 9,89 ± 2,51*** 286,44 ± 31,56***
  1. Values are means ± S.E.M., n = 5, * < 0,05, ** < 0,01, *** < 0,001, significant difference compared to the control
  2. POSM plasma osmolality