The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis: a randomized controlled trial

Table 1 General characteristics and anthropometric variables in treatment groups before and after intervention

N	Nigella sativa	Placebo	P†
N	N = 20	N = 20	P†
Age (years)	35.70 ± 8.18	33.95 ± 8.72	0.52
Levothyroxine (mcg/d)	119.85 ± 24.12	118.46 ± 22.12	0.91
Female [n (%)]	17 (85)	17 (85)	0.89
Weight (kg)
Before	70.52 ± 12.27	69.63 ± 11.75	0.81
After	69.39 11.84	69.62 11.80	0.95
P‡	0.004	0.91
BMI (kg/m2)
Before	27.10 ± 4.63	25.93 ± 4.07	0.40
After	26.63 4.42	25.95 4.11	0.61
P‡	0.002	0.65
Waist Circumference (cm)
Before	88.56 ± 7.29	88.69 ± 7.41	0.95
After	87.72 ± 6.92	88.57 ± 7.35	0.71
P‡	0.006	0.17
HC (cm)
Before	102.85 ± 6.25	101.77 ± 6.84	0.61
After	101.56 ± 5.51	101.56 ± 7.02	0.99
P‡	0.001	0.08
WHR
Before	0.86 ± 0.052	0.87 ± 0.053	0.53
After	0.86 ± 0.05	0.87 ± 4.11	0.61
P‡	0.38	0.53

BMI body mass index, WC waist circumference, HC hip circumference, WHR waist to hip ratio, †P values for ANOCOVA after adjustment for age, gender, duration of the disease and variable’s baseline value; ‡P values for paired t-test. Data are presented as mean ± SD or number (percent), the bolded P values are statistically significant

ISSN: 2662-7671