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Table 3 Efficacy of CAM antibacterial compounds on survival of E.coli 0157:H7 (1x106 CFU/ml) @ 8 h in 31 °C

From: Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis

Anti-bacterial effects of natural compounds on E. coli 0157:H7 survival
Compound LC50 Units
Penicillin/Streptomycin 0.01 Units/μg.ml
Cholloidal Silver-Argentym 23® 0.02 μg/ml
(+) Gossypol 1.5 μg/ml
Grapeseed Extract/Vitis Vinifera 1.8 μg/ml
Green Tea Extract/Camellia Sinensis 2.0 μg/ml
(-)-Epigallocatechin gallate 3.7 μg/ml
Doxorubin hydrochloride 5.4 μg/ml
Gallic Acid 8.4 μg/ml
Caffeic Acid 10.1 μg/ml
Chinese Gallnut 10.4 μg/ml
Babul Chall Bark/Acacia arabica 13.4 μg/ml
Polyphenon 60 14.1 μg/ml
Uva Ursi/Arctostaphylos uva ursi 19.1 μg/ml
Arjun/Terminalia arjuna 23.8 μg/ml
Balm of Gilead Bud/Populus candicans 26.7 μg/ml
Bayberry Root/Morella cerifera 28.5 μg/ml
Blood Root/Sanguinaria canadensis/ 33.5 μg/ml
(-)-Gallocatechin 35.8 μg/ml
2-D08 37.0 μg/ml
Glyoxal Acid 39.6 μg/ml
Scutellarian 42.0 μg/ml
Kokum Black/Garcinia Indica 47.5 μg/ml
Indole 47.5 μg/ml
Trifala 47.7 μg/ml
CraneSbill Root/Geranium maculatum 51.6 μg/ml
Shi Liu Pi (Granati Peel) 60.4 μg/ml
Catuaba Bark/Trichilia Catigua 63.4 μg/ml
Chapparal/Larrea tridentata 73.6 μg/ml
Thymol 92.0 μg/ml
Esculetin 93.3 μg/ml
Epicatechin 114.0 μg/ml
Piperonal 115.1 μg/ml
(+)-Catechin 173.0 μg/ml
  1. The data represents LC50 values determined by regression analysis, on a minimum of 6 concentrations, (n = 4)
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