TY - JOUR AU - Mazzio, Elizabeth A. AU - Li, Nan AU - Bauer, David AU - Mendonca, Patricia AU - Taka, Equar AU - Darb, Mohammed AU - Thomas, Leeshawn AU - Williams, Henry AU - Soliman, Karam F. A. PY - 2016 DA - 2016/11/15 TI - Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis JO - BMC Complementary and Alternative Medicine SP - 467 VL - 16 IS - 1 AB - Acute systemic inflammatory response syndrome arising from infection can lead to multiple organ failure and death, with greater susceptibility occurring in immunocompromised individuals. Moreover, sub-acute chronic inflammation is a contributor to the pathology of diverse degenerative diseases (Parkinson’s disease, Alzheimer’s disease and arthritis). Given the known limitations in Western medicine to treat a broad range of inflammatory related illness as well as the emergence of antibiotic resistance, there is a renewed interest in complementary and alternative medicines (CAMs) to achieve these means. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-016-1429-x DO - 10.1186/s12906-016-1429-x ID - Mazzio2016 ER -