Acupuncture with different acupoint combinations for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial

Table 2 The schedule of enrollment, interventions, and assessments

	Study period
	Enrolment	Allocation	Post-allocation						Close-out
Time points	-t1	t0	t1	t2	t3	t4	t5	t6-t20	t21
Enrollment
Eligibility screen	√
Informed consent	√
Allocation		√
Interventions
Control group
Experimental group I			√	√	√	√
Experimental group II			√	√	√	√
Experimental group III			√	√	√	√
Assessments
Baseline variables	√	√
The frequency of nausea and vomiting		√	√	√	√	√	√	√	√
The grading of nausea and vomiting		√	√	√	√	√	√	√	√
Rhodes Index of nausea, vomiting and retching		√	√	√	√	√	√	√	√
The grading of constipation and diarrhea		√					√		√
eletrogastrogram		√					√		√
quality of life		√					√		√
anxiety and depression		√					√		√
Other adverse effect during the chemotherapy							√		√
The adverse effects of acupuncture			√	√	√	√

t0, the day before chemotherapy; t1-t5, the first day to the fifth day of chemotherapy; t6-t21, the sixth day to the 21st day of chemotherapy

ISSN: 2662-7671