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Table 9 The effect of treating CCl4 induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on CAT, SOD and GSST in serum and liver tissue homogenate

From: The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Parameters Statistics G1 G2 G3 G4
N. Control P. Control Olive oil N. sativa oil
Serum Catalase (S.CAT) U/I Mean ± SE 2.77 ± 0.01a 0.13 ± 0.00 c0 1.34 ± 0.05d 2.08 ± 0.06b
LSD 0.05 = 0.438
T-test - 189.86*** −25.73*** −35.40***
Serum Superoxide dismutase (S.SOD) U/ml Mean ± SE 626.11 ± 3.88a 215.31 ± 3.15d 427.01 ± 2.99c 544.50 ± 3.87b
LSD 0.05 = 9.935
T-test - 91.91*** −58.51*** −66.38***
Serum Glutathione reductase (S.GSST) U/ml Mean ± SE 717.81 ± 2.87a 246.68 ± 2.96d 518.28 ± 2.60c 631.68 ± 3.19b
LSD 0.05 = 9.663
T-test - 99.95*** −65.26*** −88.89***
CAT U/g. Liver tissue Mean ± SE     
LSD 0.05 = 0.230 5.53 ± 0.13a .18 ± 0.01 d0 2.38 ± 0.03c 4.58 ± 0.09b
T-test - 42.97*** −64.97*** −44.43***
SOD U/g. Liver tissue Mean ± SE 815.06 ± 3.27a 213.81 ± 2.40d 628.48 ± 2.09c 745.80 ± 2.89b
LSD 0.05 = 8.575
T-test - 166.80*** −103.43*** −122.00***
GSST U/g. Liver tissue Mean ± SE 734.76 ± 84.41a 373.33 ± 58.54d 669.95 ± 14.58c 739.01 ± 3.77b
LSD 0.05 = 10.833
T-test - 2.53*** −6.69*** −6.46***
MDA nmol/ml Mean ± SE 0.39 ± 0.01d 2.85 ± 0.01a 1.50 ± 0.03b 0.88 ± 0.02c
LSD 0.05 = 0.0817
T-test - −90.44*** 40.04*** 49.20***
MDA nmol/ g. Liver tissue Mean ± SE 2.59 ± 0.12d 19.78 ± 0.37a 10.55 ± 0.37c 14.71 ± 0.17b
LSD 0.05 = 0.977
T-test - −45.43*** 13.65*** 10.84***
  1. Data are represented as mean ± SE. T-test values ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P > 0.05. LSD least significant difference