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Table 9 The effect of treating CCl4 induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on CAT, SOD and GSST in serum and liver tissue homogenate

From: The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Parameters

Statistics

G1

G2

G3

G4

N. Control

P. Control

Olive oil

N. sativa oil

Serum Catalase (S.CAT) U/I

Mean ± SE

2.77 ± 0.01a

0.13 ± 0.00 c0

1.34 ± 0.05d

2.08 ± 0.06b

LSD 0.05 = 0.438

T-test

-

189.86***

−25.73***

−35.40***

Serum Superoxide dismutase (S.SOD) U/ml

Mean ± SE

626.11 ± 3.88a

215.31 ± 3.15d

427.01 ± 2.99c

544.50 ± 3.87b

LSD 0.05 = 9.935

T-test

-

91.91***

−58.51***

−66.38***

Serum Glutathione reductase (S.GSST) U/ml

Mean ± SE

717.81 ± 2.87a

246.68 ± 2.96d

518.28 ± 2.60c

631.68 ± 3.19b

LSD 0.05 = 9.663

T-test

-

99.95***

−65.26***

−88.89***

CAT U/g. Liver tissue

Mean ± SE

    

LSD 0.05 = 0.230

5.53 ± 0.13a

.18 ± 0.01 d0

2.38 ± 0.03c

4.58 ± 0.09b

T-test

-

42.97***

−64.97***

−44.43***

SOD U/g. Liver tissue

Mean ± SE

815.06 ± 3.27a

213.81 ± 2.40d

628.48 ± 2.09c

745.80 ± 2.89b

LSD 0.05 = 8.575

T-test

-

166.80***

−103.43***

−122.00***

GSST U/g. Liver tissue

Mean ± SE

734.76 ± 84.41a

373.33 ± 58.54d

669.95 ± 14.58c

739.01 ± 3.77b

LSD 0.05 = 10.833

T-test

-

2.53***

−6.69***

−6.46***

MDA nmol/ml

Mean ± SE

0.39 ± 0.01d

2.85 ± 0.01a

1.50 ± 0.03b

0.88 ± 0.02c

LSD 0.05 = 0.0817

T-test

-

−90.44***

40.04***

49.20***

MDA nmol/ g. Liver tissue

Mean ± SE

2.59 ± 0.12d

19.78 ± 0.37a

10.55 ± 0.37c

14.71 ± 0.17b

LSD 0.05 = 0.977

T-test

-

−45.43***

13.65***

10.84***

  1. Data are represented as mean ± SE. T-test values ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P > 0.05. LSD least significant difference