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Table 8 The effect of treating CCl4 induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on serum lipid profile levels

From: The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

C

Statistics

G1

G2

G3

G4

N. Control

P. Control

Olive oil

Nigella sativa oil

TG mg/dl

Mean ± SE

115.00 ± 4.64d

244.83 ± 4.77a

218.33 ± 15.12b

181.33 ± 1.97c

LSD 0.05 = 26.170

T-test

-

−15.21***

1.50NS

9.80***

TC mg %

Mean ± SE

161.00 ± 3.06d

278.00±3.63a

227.00±2.06b

189.00±3.26c

LSD 0.05 = 8.802

T-test

-

-22.16***

15.23***

16.90***

HDL mg/dl

Mean±SE

48.33±0.42a

30.00±0.57d

40.83±0.47b

36.50±0.42c

LSD 0.05=1.554

T-test

-

24.11***

−18.02***

−7.67***

LDL mg/dl

Mean ± SE

89.33 ± 3.33d

198.50 ± 4.13a

145.50 ± 2.12b

115.83 ± 3.41c

LSD 0.05 = 9.502

T-test

-

−17.86***

15.38***

14.68***

VLDL mg/dl

Mean ± SE

23.73 ± 1.56c

48.96 ± 0.95a

43.66 ± 3.02c

36.26 ± 0.39b

LSD 0.05 = 5.595

T-test

-

−11.67***

1.50 ***

9.80***

  1. Data are represented as mean ± SE. T-test values *: significant at P < 0.05,**: significant at P < 0.01, ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P > 0.05. LSD least significant difference, N.S. non significant