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Table 6 The effect of treating CCl4 induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on liver enzymes, total proteins, albumin and total bilirubin

From: The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Liver enzymes U/l

Statistics

G1

G2

G3

G4

N. Control

P. Control

Olive oil

Nigella sativa oil

AIT

Mean ± SE

25.16 ± 1.35d

71.00 ± 1.41a

58.83 ± 0.47b

52.16 ± 1.13c

LSD0.05 = 3.275

T-test

-

−21.00***

7.15***

39.46***

AST

Mean ± SE

26.50 ± 0.76d

81.16 ± 1.66a

65.50 ± 0.99b

50.50 ± 1.11c

LSD0.05 = 2.501

T-test

-

−44.47***

10.95***

23.91***

ALP

Mean ± SE

156.66 ± 2.17d

286.16 ± 2.82a

228.50 ± 2.50b

185.50 ± 2.43c

LSD 0.05 = 8.122

T-test

-

−37.51***

14.90***

19.55***

Total protein

Mean ± SE

7.65 ± 0.04a

4.81 ± 0.09d

5.66 ± 0.04c

6.80 ± 0.05b

LSD 0.05 = 0.201

T-test

-

22.55***

−10.04***

−16.22***

Albumin

Mean ± SE

4.50 ± 0.05a

2.56 ± 0.09d

3.10 ± 0.04c

3.85 ± 0.04b

LSD 0.05 = 0.203

T-test

-

15.72***

−4.78***

−16.19***

Total Bilirubin mg/dl

Mean ± SE

0.42 ± 0.00d

1.38 ± 0.03a

0.84 ± 0.00b

0.76 ± 0.04c

LSD 0.05 = 0.077

T-test

-

−28.02***

15.58***

15.11***

  1. Data are represented as mean ± SE. T-test values ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P > 0.05. LSD least significant difference