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Table 6 The effect of treating CCl4 induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on liver enzymes, total proteins, albumin and total bilirubin

From: The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Liver enzymes U/l Statistics G1 G2 G3 G4
N. Control P. Control Olive oil Nigella sativa oil
AIT Mean ± SE 25.16 ± 1.35d 71.00 ± 1.41a 58.83 ± 0.47b 52.16 ± 1.13c
LSD0.05 = 3.275
T-test - −21.00*** 7.15*** 39.46***
AST Mean ± SE 26.50 ± 0.76d 81.16 ± 1.66a 65.50 ± 0.99b 50.50 ± 1.11c
LSD0.05 = 2.501
T-test - −44.47*** 10.95*** 23.91***
ALP Mean ± SE 156.66 ± 2.17d 286.16 ± 2.82a 228.50 ± 2.50b 185.50 ± 2.43c
LSD 0.05 = 8.122
T-test - −37.51*** 14.90*** 19.55***
Total protein Mean ± SE 7.65 ± 0.04a 4.81 ± 0.09d 5.66 ± 0.04c 6.80 ± 0.05b
LSD 0.05 = 0.201
T-test - 22.55*** −10.04*** −16.22***
Albumin Mean ± SE 4.50 ± 0.05a 2.56 ± 0.09d 3.10 ± 0.04c 3.85 ± 0.04b
LSD 0.05 = 0.203
T-test - 15.72*** −4.78*** −16.19***
Total Bilirubin mg/dl Mean ± SE 0.42 ± 0.00d 1.38 ± 0.03a 0.84 ± 0.00b 0.76 ± 0.04c
LSD 0.05 = 0.077
T-test - −28.02*** 15.58*** 15.11***
  1. Data are represented as mean ± SE. T-test values ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P > 0.05. LSD least significant difference