The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Table 3 The effect of treating CCl₄ induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on total body weight

Total body weight (g)	Statistics	G1	G2	G3	G4
Total body weight (g)	Statistics	N. Control	P. Control	Olive oil	N. sativa oil
1st week	Mean ± SE	178.66 ± 1.08 ^d	201.33 ± 0.88 ^a	190.16 ± 2.10 ^c	197.50 ± 1.11 ^b
	LSD 0.05 = 3.504	178.66 ± 1.08 ^d	201.33 ± 0.88 ^a	190.16 ± 2.10 ^c	197.50 ± 1.11 ^b
	T-test	-	−19.79^***	4.85^***	2.49^*
2nd week	Mean ± SE	181.66 ± 1.30 ^c	198.50 ± 0.95 ^ab	196.00 ± 3.10 ^b	200.83 ± 1.44 ^a
	LSD 0.05 = 4.444	181.66 ± 1.30 ^c	198.50 ± 0.95 ^ab	196.00 ± 3.10 ^b	200.83 ± 1.44 ^a
	T-test	-	−11.82^***	0.88 ^NS	−1.71 ^NS
3rd week	Mean ± SE	186.00 ± 1.29 ^c	201.16 ± 0.74 ^ab	199.50 ± 3.33 ^b	204.16 ± 1.74 ^a
	LSD 0.05 = 4.875	186.00 ± 1.29 ^c	201.16 ± 0.74 ^ab	199.50 ± 3.33 ^b	204.16 ± 1.74 ^a
	T-test	-	−10.48^***	0.56 ^NS	−1.56 ^NS
4th week	Mean ± SE	189.00 ± 1.50 ^c	203.83 ± 0.54 ^b	202.66 ± 3.06 ^b	208.50 ± 1.66 ^a
	LSD 0.05 = 4.450	189.00 ± 1.50 ^c	203.83 ± 0.54 ^b	202.66 ± 3.06 ^b	208.50 ± 1.66 ^a
	T-test	-	−8.34^***	0.39 ^NS	−2.49^*

Data are represented as mean ± SE. T-test values ^*: significant at P < 0.05, ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P> 0.05. LSD least significant difference, N.S non significant

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