Table 4 Univariate analysis of clinical characteristics and constitution scores with severe CINV
CINV [n (%)] (n = 612) | ||||
|---|---|---|---|---|
Grade 0-II (n = 339) | Grade III-IV (n = 273) | P | ||
Age | 48.5 ± 10.1 | 48.5 ± 9.7 | 0.382 | |
Education level | Junior middle school or above | 147 (43.4 %) | 103 (37.7 %) | 0.164 |
Below junior middle school | 192 (56.6 %) | 170 (62.3 %) | ||
History of breast cancer | Yes | 119 (35.1 %) | 87 (31.9 %) | 0.400 |
No | 220 (64.9 %) | 186 (68.1 %) | ||
History of vomiting | Yes | 77 (22.7 %) | 37 (13.6 %) | 0.004 |
No | 262 (77.3 %) | 236 (86.4 %) | ||
KPS score | 60–70 | 262 (77.3 %) | 215 (78.7 %) | 0.663 |
70–100 | 77 (22.7 %) | 58 (21.3 %) | ||
TNM staging | I | 62 (18.3 %) | 73 (26.7 %) | 0.030 |
II | 199 (58.7 %) | 132 (48.3 %) | ||
III | 58 (17.1 %) | 46 (16.9 %) | ||
IV | 20 (5.9 %) | 22 (8.1 %) | ||
ER | Positive | 102 (30.1 %) | 89 (32.6 %) | 0.505 |
Negative | 237 (69.9 %) | 184 (57.4 %) | ||
PR | Positive | 145 (42.8 %) | 137 (50.2 %) | 0.068 |
Negative | 194 (57.2 %) | 136 (49.8 %) | ||
HER2 | Negative | 213 (62.8 %) | 171 (62.6 %) | 0.961 |
Positive | 126 (37.2 %) | 102 (37.4 %) | ||
P21 | Negative | 259 (76.4 %) | 199 (72.9 %) | 0.320 |
Positive | 80 (23.6 %) | 74 (27.1 %) | ||
P53 | Negative | 289 (85.3 %) | 221 (81.0 %) | 0.156 |
Positive | 50 (14.7 %) | 52 (19.0 %) | ||
PCNA | Negative | 267 (78.8 %) | 206 (75.5 %) | 0.332 |
Positive | 72 (21.2 %) | 67 (24.5 %) | ||
TCM constitutions | Qi-deficiency | 21.3 ± 13.8 | 22.7 ± 14.4 | 0.439 |
Yin-deficiency | 20.3 ± 13.7 | 21.5 ± 11.5 | 0.001 | |
Wetness-heat | 14.6 ± 10.5 | 17.6 ± 12.5 | 0.012 | |
Qi-depression | 26.3 ± 16.2 | 29.4 ± 16.0 | 0.968 | |
Yang-deficiency | 18.8 ± 15.8 | 20.0 ± 16.4 | 0.341 | |
Blood-stasis | 19.3 ± 12.1 | 21.3 ± 12.4 | 0.453 | |
Phlegm-wetness | 17.3 ± 10.5 | 18.3 ± 11.5 | 0.028 | |
Gentleness | 69.0 ± 12.7 | 68.0 ± 13.7 | 0.275 | |