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Table 2 Effect of FXM on antioxidant enzymes of liver in rat

From: Protective effects of Fraxinus xanthoxyloides (Wall.) leaves against CCl4 induced hepatic toxicity in rat

Treatment

CAT (U/min)

POD (U/min)

SOD (U/mg protein)

GST (mM/min/mg protein)

GSR (mM//min/mg protein)

Control

3.88 ± 0.53ab

9.55 ± 0.99ab

3.00 ± 0.31a

160.81 ± 8.53a

224.62 ± 9.02a

DMSO + Olive oil

4.19 ± 0.27a

10.65 ± 1.44ab

3.07 ± 0.27a

158.56 ± 11.67a

220.11 ± 8.01a

CCl4

2.33 ± 0.18†c

5.31 ± 0.63†c

1.30 ± 0.23†c

100.11 ± 4.99†c

130.52 ± 9.77†d

CCl4 + silymarin (100 mg/kg)

3.88 ± 0.28ab

9.31 ± 0.67ab

2.93 ± 0.23ab

151.02 ± 9.49ab

180.88 ± 9.17†c

CCl4 + FXM (200 mg/kg)

2.64 ± 0.15†c

7.45 ± 0.39†b

1.58 ± 0.11†c

133.85 ± 8.34†b

184.83 ± 8.90†c

CCl4 + FXM (400 mg/kg)

3.37 ± 0.24*b

9.01 ± 0.55ab

2.46 ± 0.19≠b

150.70 ± 8.98ab

198.03 ± 10.64†bc

FXM (200 mg/kg)

3.79 ± 0.23ab

9.44 ± 0.87ab

2.99 ± 0.18a

159.57 ± 9.57a

221.17 ± 7.15a

FXM (400 mg/kg)

3.91 ± 0.45ab

9.59 ± 0.75ab

2.94 ± 0.20ab

159.66 ± 9.63a

216.03 ± 8.42ab

  1. FXM F. xanthoxyloides methanol extract. Data values shown represent mean ± SD (n = 6). One way analysis of variance was followed by Dunnet comparison of various treatments with control at: *, P < 0.05; #, P < 0.01; ǂ, P < 0.001. Multiple comparisons among treatments were determined by Tukeys’ HSD test. Superscript alphabets indicate significance among treatments (P < 0.01) on not sharing common letter