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Table 1 IC50s of oxaliplatin in HCT116 and A549 cancer cells in the absence and presence of WLR treatment

From: Aqueous extract of Lithospermi radix attenuates oxaliplatin-induced neurotoxicity in both in vitro and in vivo models

Treatment

IC50s (μg/mL)

HCT116

A549

L-OHP

1.05 ± 0.07

6.94 ± 0.78

L-OHP + Vehicle

0.97 ± 0.01

5.83 ± 0.02

L-OHP + WLR (10 μg/mL)

0.98 ± 0.06

6.76 ± 0.00

L-OHP + WLR (30 μg/mL)

1.00 ± 0.02

7.66 ± 1.25

L-OHP + WLR (100 μg/mL)

0.98 ± 0.02

6.50 ± 0.30