Fig. 2

The mitigative effect of Douchi treatment for AD symptoms. The skin features demonstrated visually a marked reduction in DT compared with AD. Incision of red box is analyzed to identify capillary distribution. In our image analysis of the capillaries, the size and branch of capillary increased in the AD, but decreased in the DT (4×). In H&E result, red spot indicates capillary, ↕: hyperplasia of the epithelium. *: p < 0.01 compared with AD, #: p < 0.01 compared with Ctrl. Bar size: 200 μm (Figure in H&E). Abbreviations; AD: AD-induced mice, Ctrl: non treatment mice, DT: Douchi extract-treated mice after AD inducement, Der: dermis, Epi: epidermis, H&E: Haematoxylin and eosin stain, Sub: subcutaneous layer