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Table 3 The percentage of maximum possible effect (%MPE) of MECC in hot plate test

From: Antinociceptive effect of methanol extract of Celosia cristata Linn. in mice

Treatment

Dose (mg/kg)

%MPE

30 min

45 min

60 min

90 min

120 min

Vehicle

-

-2.49 ± 6.47

5 ± 9.24

7.44 ± 5.44

5.17 ± 11.70

5.73 ± 6.69

NLX

2 (i.p.)

6.06 ± 2.50

5.51 ± 1.26

6.11 ± 2.00

4.98 ± 2.68

5.73 ± 3.64

MECC

50

6.97 ± 1.42

15.66 ± 4.85

29.61 ± 3.22*

36.02 ± 1.36*

28.39 ± 4.16

MECC

100

14.19 ± 3.03

25.32 ± 2.50*

39.07 ± 1.87*

40.98 ± 5.99*

35.26 ± 3.02*

MECC

200

23.64 ± 3.90*

34.04 ± 3.14*

43.02 ± 2.17*

51.43 ± 2.24*

40.01 ± 5.62*

MECC

400

29.62 ± 1.23*

46.24 ± 1.89*

55.36 ± 3.67*

60.06 ± 3.28*

43.48 ± 4.83*

Morphine

5 (i.p.)

32.07 ± 3.64*

47.89 ± 3.68*

59.14 ± 3.26*

66.27 ± 2.18*

45.24 ± 10.25*

  1. Each value is presented as the mean ± SEM (n = 5). MECC = Methanol extract of C. cristata; NLX = Naloxone. * represents p < 0.001 compared with the control group (Dunnett’s test)