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Fig. 8 | BMC Complementary and Alternative Medicine

Fig. 8

From: The antifibrotic and fibrolytic properties of date fruit extract via modulation of genotoxicity, tissue-inhibitor of metalloproteinases and nuclear factor- kappa B pathway in a rat model of hepatotoxicity

Fig. 8

Light microscopic photomicrographs of liver tissue immunostained with primary anti COX-2 antibody (Scale bar = 50 μm). Panel a represents liver section from control rat showing very faint or weak immune-reactivity of hepatocytes, while panel b represents liver section of rat received CCl4 in which strong abnormal irregularly distributed immune reactivity was observed, especially between degenerated hepatocytes’ cytoplasm and nuclei (arrow). Many nuclei are also positively stained (arrow). Panels c d and e represent liver sections from rats treated with DFE, DPE and coffee, respectively showing marked decrease of the intensity of the immune reactivity of hepatocytes surrounding portal areas especially in rats treated with DFE (arrows)

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