Moxibustion treatment for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized controlled trial

Table 1 Trial flowchart

Items		Before enrolment (weeks) –4 to 0	Intervention period (weeks) 1–6	End of 6-week treatment (weeks)	Follow-up (weeks) 7–12	End of 12-week follow-up (weeks)	Follow-up (weeks) 13–18	End of 18-week follow-up (weeks)
Recruitment		×
Enrolment		×
Inclusion criteria		×
Exclusion criteria		×
Informed consent		×
Basic characteristic variables		×
Randomization and allocation concealment		×
Primary outcomes	AR		×	×	×	×	×	×
Secondary outcomes	SSS	×		×		×		×
	BSS	×		×		×		×
	IBS-QOL	×		×
	HADS	×		×
Safety outcome				×		×		×
Statistical analysis				×		×		×

ISSN: 2662-7671