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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Estrogenic and cytotoxic potentials of compounds isolated from Millettia macrophylla Benth (Fabaceae): towards a better understanding of its underlying mechanisms

Fig. 4

Effects of stigmastenone (3) and M. macrophylla phenolic fraction (PF) on the activation of estrogen α and β receptors in HEK293T cells. The effect of these substances on estrogen α and β receptors activity in the transiently transfected HEK293T-ERα and HEK293T-ERβ cells was investigated by measuring reporter gene-coupled luciferase activity. The relative luciferase units (RLU) were measured in the presence of EtOH (0.1 %), E2 (10 nM), stigmatenone (3) as well as M. macrophylla phenolic fraction co-treated with E2. ** p < 0.01; *** p < 0.001 as compared to EtOH control; ### p < 0.001 as compared with E2 control

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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