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Table 1 The IC50 values of ESG, rosmarinic acid (RA), astilbin (AS), and the positive controls

From: Sarcandra glabra (Caoshanhu) protects mesenchymal stem cells from oxidative stress: a bioevaluation and mechanistic chemistry

Assays ESG μg/mL RA μg/mL (μM) AS μg/mL (μM) Positive controls
Trolox μg/mL (μM) BHA μg/mL (μM)
DNA protective effect 79.9 ± 10.4 44.9 ± 8.9
(126.7 ± 23.1b)
70.9 ± 1.6
(193.3 ± 5.8c)
85.0 ± 21.3
(85.0 ± 21.3a)
67.8 ± 12.4
(376.3 ± 69.2d)
•OH scavenging 109.5 ± 4.5 100.7 ± 0.9
(280.0 ± 1.0b)
97.9 ± 5.5
(220.0 ± 10.0a)
110.0 ± 4.6
(441.0 ± 20.1d)
63.3 ± 7.8
(353.3 ± 41.6c)
•O2 scavenging 140.8 ± 3.1 18.4 ± 0.4
(50 ± 0.4a)
132.8 ± 3.4b
(295.0 ± 7.5b)
167.3 ± 11.1
(668.3 ± 40.2c)
146.6 ± 4.4
(813.0 ± 24.0d)
FRAP 24.9 ± 1.0 7.1 ± 1.2
(19.6 ± 3.2b)
5.4 ± 0.2
(12.0 ± 0.4a)
6.9 ± 0.3
(27.6 ± 1.2c)
4.4 ± 0.2
(24.0 ± 1.1c)
ABTS+• scavenging 12.1 ± 1.8 6.8 ± 0.4
(18.7 ± 2.1b)
5.0 ± 0.7
(11.1 ± 1.7a)
7.2 ± 0.1
(29.0 ± 0.1c)
5.9 ± 0.1
(33.3 ± 0.1c)
DPPH• scavenging 48.6 ± 0.3 1.3 ± 0.1
(4.0 ± 0.1a)
8.7 ± 0.2
(19.7 ± 5.8d)
1.5 ± 0.1
(6.2 ± 0.1b)
1.9 ± 0.1
(10.8 ± 0.3c)
Fe2+ chelating 134.2 ± 15.6 128.1 ± 10.4
(355.7 ± 29.1b)
218.8 ± 11.0
(485.0 ± 21.2c)
63.9 ± 4.4
(217.3 ± 15.3a)d
ND
  1. IC50 value is defined as the concentration of 50 % effect percentage and expressed as mean ± SD (n = 3). Means values with different superscripts (a, b) in the same row are significantly different (p < 0.05), while with same superscripts are not significantly different (p < 0.05). dThe positive control is sodium citrate. BHA butylated hydroxyanisole, ESG Ethanolic extract of Sarcandra glabra (Thunb.) Nakai, ND Cannot be detected, FRAP ferric ion reducing antioxidant power