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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: The ethyl acetate fraction of corn silk exhibits dual antioxidant and anti-glycation activities and protects insulin-secreting cells from glucotoxicity

Fig. 3

Evaluation of YMS-EA and reference drugs against acute H2O2 challenge mediated anti-proliferation and apoptosis in BRIN-BD11 cells. a BRIN-BD11 cells were treated with H2O2 for 2 h, and then the medium was replaced with culture medium. The cell proliferation assay (WST-1) was performed at 0, 6, 12, 24, 36, and 48 h. Data are mean ± SEM (n = 8). ap < 0.05, bp < 0.01, cp < 0.001 versus time 0. b Cell proliferation activity at the end of 48 h in the culture medium with YMS-EA (100 μg/ml), AG (2 mM), Met (100 μM) or Trox (100 μM) after acute H2O2 (250 μM) challenge. Data are mean ± SEM (n = 8). ap < 0.05, bp < 0.01, cp < 0.001 versus no treatment after H2O2 challenge. c The population of necrotic or apoptotic cells was evaluated at 24 h after acute H2O2 (250 μM) challenge. Data are mean ± SEM (n = 4). bp < 0.01, cp < 0.001 versus the corresponding population with no treatment after H2O2 challenge. d Apoptotic cell population in the presence of test agents at 24 h after H2O2 (250 μM) challenge. Data are mean ± SEM (n = 4)

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