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Table 2 Histopathological scoring system for nonalcoholic fatty liver disease (NAFLD) [17]

From: Protective effects of saffron extract and crocin supplementation on fatty liver tissue of high-fat diet-induced obese rats

Component

Grade 0

Grade 1

Grade 2

Grade 3

Range

Steatosis

<5 %

5–33 %

34–66 %

>67 %

0–3

Hepatocyte ballooning

0

Few

Many

N/A

0–2

Lobular inflammation

0

<2 foci/ 20×

2–4

>4

0–3

NAFLD activity score (NAS)

0–8